Treatment Options for Osteosarcoma
How Treatments Are Selected
Specific treatment for osteosarcoma will be determined by your physician based on:
- Your age, overall health, and medical history
- Extent of the disease
- Your tolerance for specific medications, procedures, or therapies
- Expectations for the course of the disease
- Your opinion or preference
Types of Treatments
Treatment may include:
- Surgery (i.e., biopsy, resections, bone/skin grafts, limb salvage procedures, reconstructions)
- Amputation
- Chemotherapy
- Radiation therapy
- Resections of metastases (spreading of the tumor to other locations)
- Rehabilitation, including physical and occupational therapy, and psychosocial adapting
- Prosthesis fitting and training
- Supportive care for the side effects of treatment
- Antibiotics to prevent and treat infections
Continued follow-up care to determine response to treatment, detect recurrent disease, and manage the side effects of treatment. Many patients, particularly those with higher-grade tumors, will receive a combination of treatments.

