Major Areas of Research
Methodology
Program researchers conduct ongoing methodological studies to monitor the quality and consistency of data in the SEER registries, which are obtained from medical records and submitted to the Cancer Prevention Institute of California from a number of different sources. Special areas of interest include data on race, ethnicity, nativity and socioeconomic status, which are critical to addressing health disparities in under-served population subgroups. These methodological studies provide information that can help hospitals and other medical facilities improve the consistent reporting of patient data.
Alice Whittemore, Ph.D., and Gail Gong, Ph.D., of Stanford University School of Medicine, used computer simulations to compare the performance of two study designs based on family data for estimating the disease risk associated with mutations of known disease-susceptibility genes. The scientists found that clinic-based designs, where families are ascertained because they meet certain criteria for multiple disease occurrence in the family, yielded more accurate estimates than did population-based designs, where families are sampled through population-based registries of affected individuals. The reason may be that clinic-based designs include more identified mutation carriers. The study was conducted with assistance from the EGRP-funded Cancer Family Registries. Investigators are also working to enhance the utility of SEER by linking its data sets to those of Medicare and other databases.
Dr Abby King (SPRC) has, in collaboration with investigators from Boston Medical Center and M.I.T., obtained NCI funding to conduct research on a computer-based ecological momentary assessment of physical activity in work and home environments, which is a series of studies to develop and evaluate state-of-the-art electronic systems for simultaneously recording objective and subjective daily and routine activity in underserved populations.
Areas of Special Interest Include:| Bioinformatics | |
| Cancer Epidemiology Program Members: | Researchers: Russ Altman, Ronald Davis, Sylvia Plevritis |
| Data Integrity and Quality Assurance | |
| Seer Data Collection Enhancement | Cancer Epidemiology Program Members: | Researchers: Scarlett Gomez, Esther John, Dee West |
| Subject Ascertainment | |
| Cancer Epidemiology Program Members: | Researchers: Esther John, Philip Lavori, Dee West, Alice Whittemore |
| Economic Analysis | |
| Cancer Epidemiology Program Members: | Researchers: Gary Friedman, Lisa Henriksen, Mark Hlatky, Douglas Owens, Silvia Plevritis | Cancer Prevention and Control Program Members: | Researchers: Michael Gould, Joseph Presti, Todd Wagner |
| Graphical Information Systems Integration | |
| Cancer Epidemiology Program Members: | Researchers: Scarlett Gomez, Peggy Reynolds, Rudy Rull |
| Statistical Analysis | |
| Genetic Analysis | |
| Linkage Analysis | |
| Cancer Epidemiology Program Members: | Researchers: Laura Lazzeroni, Richard Olshen, Weiva Sieh, Alice Whittemore |
| Genome Wide Association Methods | |
| Cancer Epidemiology Program Members: | Researchers: Ronald Davis, Alice Whittemore |
| Microarray Analysis Design | |
| Cancer Epidemiology Program Members: | Researchers: Ronald Davis, Laura Lazzerroni, Sylvia Plevritis |
| Risk Analysis | |
| Cancer Epidemiology Program Members: | Researchers: Alice Whittemore |
| Surveillance Modeling | |
| Cancer Epidemiology Program Members: | Researchers: Sylvia Plevritis, David Nelson |
| Study Instrument Design | |
| Questionnaire Development | |
| Cancer Prevention and Control Program Members: | Researchers: Michaela Kiernan, Ingrid Oakley-Girvan |
| Quality of Life Instruments | |
| Cancer Prevention and Control Program Members: | Researchers: David Spiegel, Randall Stafford, Marcia Stefanick, Marilyn Winkleby |
| Nutritional Evaluation Instruments | |
| Cancer Epidemiology Program Members: | Researchers: Pamela Horn-Ross | Cancer Prevention and Control Program Members: | Researchers: Alan Gardner |
| Physical Activity Evaluation Instruments | |
| Cancer Prevention and Control Program Members: | Researchers: Abby King, Macria Stefanick |
| Treatment Modalities | |
| Cancer Prevention and Control Program Members: | Researchers: Robert Carlson, Stephen Fortmann, Michael Gould, Joel Killen, Richard Olshen, Joseph Presti |
This document was last modified: Tuesday, 27-Sep-2011 21:47:51 PDT
Trial Administration