Cancer Institute A national cancer institute
designated cancer center

Major Areas of Research

Methodology

Program researchers conduct ongoing methodological studies to monitor the quality and consistency of data in the SEER registries, which are obtained from medical records and submitted to the Cancer Prevention Institute of California from a number of different sources. Special areas of interest include data on race, ethnicity, nativity and socioeconomic status, which are critical to addressing health disparities in under-served population subgroups. These methodological studies provide information that can help hospitals and other medical facilities improve the consistent reporting of patient data.

Alice Whittemore, Ph.D., and Gail Gong, Ph.D., of Stanford University School of Medicine, used computer simulations to compare the performance of two study designs based on family data for estimating the disease risk associated with mutations of known disease-susceptibility genes. The scientists found that clinic-based designs, where families are ascertained because they meet certain criteria for multiple disease occurrence in the family, yielded more accurate estimates than did population-based designs, where families are sampled through population-based registries of affected individuals. The reason may be that clinic-based designs include more identified mutation carriers. The study was conducted with assistance from the EGRP-funded Cancer Family Registries. Investigators are also working to enhance the utility of SEER by linking its data sets to those of Medicare and other databases.

Dr Abby King (SPRC) has, in collaboration with investigators from Boston Medical Center and M.I.T., obtained NCI funding to conduct research on a computer-based ecological momentary assessment of physical activity in work and home environments, which is a series of studies to develop and evaluate state-of-the-art electronic systems for simultaneously recording objective and subjective daily and routine activity in underserved populations.

Areas of Special Interest Include:

Bioinformatics
Cancer Epidemiology Program Members: Researchers: Russ Altman, Ronald Davis, Sylvia Plevritis
Data Integrity and Quality Assurance
        Seer Data Collection Enhancement
Cancer Epidemiology Program Members: Researchers: Scarlett Gomez, Esther John, Dee West
       Subject Ascertainment
Cancer Epidemiology Program Members: Researchers: Esther John, Philip Lavori, Dee West, Alice Whittemore
Economic Analysis
Cancer Epidemiology Program Members: Researchers: Gary Friedman, Lisa Henriksen, Mark Hlatky, Douglas Owens, Silvia Plevritis
Cancer Prevention and Control Program Members: Researchers: Michael Gould, Joseph Presti, Todd Wagner
Graphical Information Systems Integration
Cancer Epidemiology Program Members: Researchers: Scarlett Gomez, Peggy Reynolds, Rudy Rull
Statistical Analysis
       Genetic Analysis
               Linkage Analysis
Cancer Epidemiology Program Members: Researchers: Laura Lazzeroni, Richard Olshen, Weiva Sieh, Alice Whittemore
               Genome Wide Association Methods
Cancer Epidemiology Program Members: Researchers: Ronald Davis, Alice Whittemore
               Microarray Analysis Design
Cancer Epidemiology Program Members: Researchers: Ronald Davis, Laura Lazzerroni, Sylvia Plevritis
       Risk Analysis
Cancer Epidemiology Program Members: Researchers: Alice Whittemore
       Surveillance Modeling
Cancer Epidemiology Program Members: Researchers: Sylvia Plevritis, David Nelson
Study Instrument Design
       Questionnaire Development
Cancer Prevention and Control Program Members: Researchers: Michaela Kiernan, Ingrid Oakley-Girvan
       Quality of Life Instruments
Cancer Prevention and Control Program Members: Researchers: David Spiegel, Randall Stafford, Marcia Stefanick, Marilyn Winkleby
       Nutritional Evaluation Instruments
Cancer Epidemiology Program Members: Researchers: Pamela Horn-Ross
Cancer Prevention and Control Program Members: Researchers: Alan Gardner
       Physical Activity Evaluation Instruments
Cancer Prevention and Control Program Members: Researchers: Abby King, Macria Stefanick
Treatment Modalities
Cancer Prevention and Control Program Members: Researchers: Robert Carlson, Stephen Fortmann, Michael Gould, Joel Killen, Richard Olshen, Joseph Presti

 

This document was last modified: Tuesday, 27-Sep-2011 21:47:51 PDT

Stanford Medicine Resources:

Footer Links: