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Research Programs
Core Facilities

The Stanford Cancer Center provides expert support services and state-of-the-art equipment to all Cancer Center members through a number of core facilities. Each facility conducts its own research and development efforts to ensure that investigators have access to the most sophisticated technologies and research protocols available today.

Animal Tumor Models and Histopathology Facility

The Animal Tumor Models and Pathology Core Facility supports state-of-the-art in vivo tumor biology research through a number of specialized services, including animal tumor modeling, experimental pathology, clinical diagnostics, embryo cryopreservation/rederivation and assisted reproduction. The facility additionally ensures the effectiveness of these studies through the standardization of drug injections, tumor inoculations and other technical procedures. More

Cancer Biostatistics Core

The Biostatistics Facility provides statistical support to assist researchers at each stage of a study’s lifecycle, including project design, mid-study evaluation and the interpretation and reporting of results. The facility also assists with the statistical review of proposed studies and the planning of research-related data management systems. All services are provided under the direction of the Division of Biostatistics within the Department of Health Research and Policy. More

Cancer Imaging Core

The Cancer Imaging Core supports the in vivo structural and functional analysis of animal models of cancer through state-of-the-art imaging instrumentation and variety of services. Existing technologies include a number of in vivo optical bioluminescence/fluorescence imaging systems offering 3D images of cellular and molecular processes. As part of the Molecular Imaging Program at Stanford (MIPS), the core also serves as a test bed for advances in molecular imaging that have preclinical and clinical applications. More

Cell Sciences Imaging Facility (CSIF)

The Cell Sciences Imaging Facility (CSIF) supports Cancer Center investigations into the molecular and cellular mechanisms of cancer through a number of state-of-the-art imaging services. Available technologies include confocal laser scanning fluorescence microscopy, 2-photon fluorescence microscopy, digital image restoration methods, immunoelectron microscopy and multi-dimensional (3D, 4D) imaging technology for volumetric analysis of cell and tissue architecture. The facility also offers ongoing training in instrumentation use and techniques. More

Clinical Protocol and Data Management Facility

The Clinical Protocol and Data Management Facility provides critical support services to all Cancer Center investigators conducting clinical trials, including administrative support for protocol development, budget preparation and other oversight requirements. The facility additionally oversees the management of the Oncore database, procedural training for all research personnel and clinical trial recruitment. More

DNA Microarray Core Facility

The DNA Microarray Core Facility (DMCF) advances the study of gene expression across all facets of cancer development and treatment. Its cutting-edge microarray technology and analysis services combine the resources of the Stanford Microarray Database, the largest and mostly widely used public microarray database, and the Stanford Functional Genomics Facility, a leader in the development of novel genomics technologies. More

Flow Cytometry Facility

Many of the projects conducted by Cancer Center investigators depend on the fluorescence- activated cell sorter (FACS), a technology invented at Stanford in the late 1960s. Today the FACS facility provides high-volume cell analysis and cell sorting services as well as training in state-of the-art experiment design and evaluation. Ongoing efforts to advance the capabilities of FACS instrumentation ensure Cancer Center researchers have access to the most sophisticated technologies available today. More

High-throughput Bioscience Center (HTBC)

The High-throughput Bioscience Center (HTBC) provides researchers with the ability to run high-throughput chemical and genetic screens of biological systems. Utilizing the HTBC, Cancer Center members have the opportunity to discover chemical modulators of oncogenic mechanisms and to identify new therapeutic targets. More

Tissue Procurement Facility

The Tissue Procurement Facility (TPF) provides tumor tissues for a wide range of cancer-related genomic and proteomic research. TPF activities include collecting and banking freshly frozen tumor and normal tissue acquired during surgery or autopsy, providing fresh tumor tissue for viable cell studies, processing and banking serum specimens from cancer patients, maintaining a tissue database with links to clinicopathological data, providing histological staining and pathological review and coordinating patient consent and regulatory compliance. More

Transgenic and Knockout Mouse Core Facility

The Transgenic and Knockout Mouse Core Facility builds on ongoing technological breakthroughs in the transgenic field to provide powerful mouse models for in vivo studies of cancer causation and pathogenesis. The facility’s spectrum of services includes mouse embryo and stem cell manipulation, microinjection-timed pregnancies and more. More

Proteomics Shared Resource

The Stanford Proteomic Shared Resource provides state-of-the-art, user-friendly facilities and services in addition to education, methods development and new applications development designed to meet the rapidly evolving needs of Cancer Center investigators. Services include peptide and protein identification, characterization of post-translational modifications, protein quantification, biomarker verification and metabolic studies. More