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David Miklos

Academic Appointments

  • Assistant Professor of Medicine (Blood and Marrow Transplantation) at the Stanford University Medical Center

Key Documents

Contact Information

  • Clinical Offices
    Blood and Marrow Transplantation 875 Blake Wilbur Dr MC 5825 Rm 2315 Stanford, CA 94305
    Tel Work (650) 723-0822 Fax (650) 724-6182
  • Academic Offices
    Personal Information
    Email
    Administrative Contact
    Sara Clark Administrative Associate Tel Work 650-725-4959
    Not for medical emergencies or patient use

Professional Overview

Bio

I am a physician-scientist who has established a human translational research group that fosters the development of young researchers to excel as both laboratory immunologists, and clinical translational researchers. Allogeneic hematopoietic stem cell transplantation (HSCT) can cure hematologic malignancies. In an effort to discover beneficial graft-v-tumor minor histocompatibility antigens and distinguish from detrimental graft-v-host disease(GVHD) mHA, the Miklos lab has pioneered protein microarray technologies screening for allogeneic antibodies, especially H-Y antigens following sex mismatched transplantation. Our observation that allogeneic HY antibodies develop in association with chronic GVHD has supported a series of clinical trials testing rituximab cGVHD therapy. More recently, we have applied high throughput sequencing B and T cell VDJ receptor sequences enabling: 1) lymphoid disease quantification, 2) detailed B and T cell donor reconstitution kinetics, and 3) clonal analysis of antigen specific responses following allo-HCT.

Clinical Focus

  • Blood and Marrow Transplant
  • Hematology
  • Blood and Marrow Transplantation
  • Graft vs Host Disease
  • Leukemia
  • Lymphoma
View All 7clinical focus of David Miklos

Administrative Appointments

  • Medical Director of Stanford Cellular Therapeutics and Transplantation Laboratory, Stanford University (2011 - present)
  • Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease, NIH (2004 - present)

Honors and Awards

  • Clinical Investigator Training Program Scholar, Harvard Medical School (2001-2003)
  • Medical Scientist Training Fellow, NIH (1993-1995)
  • Predoctoral Fellow, Howard Hughes Medical Institute (1989-1993)
  • Alpha Omega Alpha, Yale Medical School (1995)
  • Phi Betta Kappa, University of Notre Dame (1987)

Professional Education

Residency: Brigham and Women's Hospital Harvard Medical School MA (1998)
Internship: Brigham and Women's Hospital Harvard Medical School MA (1996)
Fellowship: Dana-Farber Cancer Institute MA (2001)
Medical Education: Yale University CT (1995)
B.S.: University of Notre Dame (1987)
M.D.: Yale University Medical School (1995)
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Courses

2013-14

Prior Year Coursescourses of David Miklos

Postdoctoral Advisees

Hideki NakasoneElie Richa

Graduate and Fellowship Program Affiliations

Scientific Focus

Current Research and Scholarly Interests

I am a physician-scientist who has established a human translational research group that fosters the development of young researchers to excel as both laboratory immunologists, and clinical translational researchers. Allogeneic hematopoietic stem cell transplantation (HSCT) can cure hematologic malignancies. In an effort to discover beneficial graft-v-tumor minor histocompatibility antigens and distinguish from detrimental graft-v-host disease(GVHD) mHA, the Miklos lab has pioneered protein microarray technologies screening for allogeneic antibodies, especially H-Y antigens following sex mismatched transplantation. Our observation that allogeneic HY antibodies develop in association with chronic GVHD has supported a series of clinical trials testing rituximab cGVHD therapy. More recently, we have applied high throughput sequencing B and T cell VDJ receptor sequences enabling: 1) lymphoid disease quantification, 2) detailed B and T cell donor reconstitution kinetics, and 3) clonal analysis of antigen specific responses following allo-HCT.

Publications

Publication tag cloud

Publication Topics

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