{"result":[{"lastName":"Cleary","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4506&type=small&showNoImage","displayName":"Michael Cleary","firstName":"Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/Michael_Cleary","researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer."},{"lastName":"Chaudhuri","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23056&type=small&showNoImage","displayName":"Aadel Chaudhuri","firstName":"Aadel","href":"http://med.stanford.edu/profiles/cancer/researcher/Aadel_Chaudhuri","researchInterest":""},{"lastName":"O'Gorman","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18089&type=small&showNoImage","displayName":"William O'Gorman","firstName":"William","href":"http://med.stanford.edu/profiles/postdocs/researcher/William_O'Gorman","researchInterest":""},{"lastName":"Seita","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute"}],"primaryAppointment":"Instructor,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10040&type=small&showNoImage","displayName":"Jun Seita","firstName":"Jun","href":"http://med.stanford.edu/profiles/cancer/researcher/Jun_Seita","researchInterest":""},{"lastName":"Sahoo","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10888&type=small&showNoImage","displayName":"Debashis Sahoo","firstName":"Debashis","href":"http://med.stanford.edu/profiles/cancer/researcher/Debashis_Sahoo","researchInterest":""},{"lastName":"Parnes","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","displayName":"Jane Parnes","firstName":"Jane","href":"http://med.stanford.edu/profiles/cancer/researcher/Jane_Parnes","researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity. B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor. We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance. We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease."},{"lastName":"Tang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=16681&type=small&showNoImage","displayName":"Yujie Tang","firstName":"Yujie","href":"http://med.stanford.edu/profiles/postdocs/researcher/Yujie_Tang","researchInterest":""},{"lastName":"Chiang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stem Cell"}],"primaryAppointment":"Postdoctoral Research fellow, Stem Cell","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=24223&type=small&showNoImage","displayName":"HyoJin Chiang","firstName":"HyoJin","href":"http://med.stanford.edu/profiles/postdocs/researcher/HyoJin_Chiang","researchInterest":""},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/cancer/researcher/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Mancini","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18945&type=small&showNoImage","displayName":"Elena Mancini","firstName":"Elena","href":"http://med.stanford.edu/profiles/postdocs/researcher/Elena_Mancini","researchInterest":""},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23069&type=small&showNoImage","displayName":"Shenglin Huang","firstName":"Shenglin","href":"http://med.stanford.edu/profiles/postdocs/researcher/Shenglin_Huang","researchInterest":""},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/cancer/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Clarke","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology (Cancer)"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","displayName":"Michael F. Clarke, M.D.","firstName":"Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/Michael_Clarke","researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine. In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa"},{"lastName":"Chang","clinicalFocus":[{"focus":"Dermatology"},{"focus":"General Dermatology"}],"appointments":[{"appointment":"Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","displayName":"Howard Y. Chang","firstName":"Howard","href":"http://med.stanford.edu/profiles/cancer/researcher/Howard_Chang","researchInterest":"Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging."},{"lastName":"Wong","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Skin Cancer"},{"focus":"Teledermatology"}],"appointments":[{"appointment":"Clinical Assistant Professor,Dermatology"}],"primaryAppointment":"Clinical Assistant Professor,Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7991&type=small&showNoImage","displayName":"David J. Wong, M.D., Ph.D.","firstName":"David","href":"http://med.stanford.edu/profiles/cancer/researcher/David_Wong","researchInterest":"My research interest is focused on investigating the molecular networks that underlie cancer stem cells and designing therapies that selectively target these cells, thereby eliminating a cancer's potential for regrowth."},{"lastName":"Winslow","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=24603&type=small&showNoImage","displayName":"Monte Winslow","firstName":"Monte","href":"http://med.stanford.edu/profiles/cancer/researcher/Monte_Winslow","researchInterest":"Our laboratory uses genome-wide methods to uncover alterations that drive cancer progression and metastasis in genetically-engineered mouse models of human cancers. We combine cell-culture based mechanistic studies with our ability to alter pathways of interest during tumor progression in vivo to better understand each step of metastatic spread and to uncover the therapeutic vulnerabilities of advanced cancer cells."},{"lastName":"Zheng","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Postdoctoral Research fellow, Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=19342&type=small&showNoImage","displayName":"Grace Zheng","firstName":"Xinying","href":"http://med.stanford.edu/profiles/postdocs/researcher/Xinying_Zheng","researchInterest":""},{"lastName":"Kuo","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=5906&type=small&showNoImage","displayName":"Calvin Kuo","firstName":"Calvin","href":"http://med.stanford.edu/profiles/cancer/researcher/Calvin_Kuo","researchInterest":"We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism. Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy. Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells. We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery."},{"lastName":"Lacayo","clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant, Pediatric"},{"focus":"Oncology (Cancer), Pediatric"},{"focus":"AML, childhood and adolescent/young adult"},{"focus":"ALL, childhood and adolescent/young adult"},{"focus":"lymphoblastic lymphoma, childhood"},{"focus":"Hematology/Oncology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pediatrics - Hematology & Oncology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pediatrics - Hematology & Oncology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=5921&type=small&showNoImage","displayName":"Norman J. Lacayo, MD","firstName":"Norman","href":"http://med.stanford.edu/profiles/cancer/researcher/Norman_Lacayo","researchInterest":"Pediatric Hematology/Oncology, Phase I drug studies for refractory and relapsed leukemia; genomic studies, biologic risk-stratification and treatment of acute myeloid leukemia; prediction or induction response and risk of relapse using phosphoproteomics in childhood AML; novel MRD techniques in childhood ALL."},{"lastName":"Michie","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4707&type=small&showNoImage","displayName":"Sara Michie","firstName":"Sara","href":"http://med.stanford.edu/profiles/cancer/researcher/Sara_Michie","researchInterest":"Lymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules."},{"lastName":"Spitale","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Postdoctoral Research fellow, Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13955&type=small&showNoImage","displayName":"Robert Spitale","firstName":"Robert","href":"http://med.stanford.edu/profiles/postdocs/researcher/Robert_Spitale","researchInterest":""},{"lastName":"Zhang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23989&type=small&showNoImage","displayName":"Rui Zhang","firstName":"Rui","href":"http://med.stanford.edu/profiles/postdocs/researcher/Rui_Zhang","researchInterest":"My goal is to combine theoretical and experimental approaches to uncover the mystery of gene regulatory networks. My current research focuses on the fine-tuning function of RNA editing, a post-transcriptional-processing mechanism that contributes to the diversity of gene products."}]}