{"result":[{"lastName":"Giacomini","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"},{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=17885&type=small&showNoImage","displayName":"Craig Giacomini","firstName":"Craig","href":"http://med.stanford.edu/profiles/cancer/researcher/Craig_Giacomini","researchInterest":""},{"lastName":"van de Rijn","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Sarcoma"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4008&type=small&showNoImage","displayName":"Matt van de Rijn","firstName":"Matt","href":"http://med.stanford.edu/profiles/cancer/researcher/Matt_van de Rijn","researchInterest":"Our research focuses on gene microarray analysis of human soft tissue tumors (sarcomas). In addition we work with tissue microarrays to characterize large numbers of novel antisera raised against peptides derived from genes found to be of interest during gene array analysis."},{"lastName":"Tibshirani","clinicalFocus":[],"appointments":[{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Natural Sciences Cluster - Statistics"}],"primaryAppointment":"Professor,Health Research & Policy - Biostatistics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4688&type=small&showNoImage","displayName":"Robert Tibshirani","firstName":"Robert","href":"http://med.stanford.edu/profiles/cancer/researcher/Robert_Tibshirani","researchInterest":"My research is in applied statistics and biostatistics. I specialize in \u000bcomputer-intensive methods for regression and classification, bootstrap, cross-validation\u000band statistical inference, and signal and image analysis for medical diagnosis."},{"lastName":"Brooks","clinicalFocus":[{"focus":"Male Cancers - Prostate "},{"focus":"Prostate Cancer"},{"focus":"Nerve-sparing radical prostatectomy"},{"focus":"Prostate Cancer - Urologic Oncology"},{"focus":"Urologic Cancers"},{"focus":"Urologic Cancers - Urologic Oncology"},{"focus":"Urology"}],"appointments":[{"appointment":"Professor,Urology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Urology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6178&type=small&showNoImage","displayName":"James D. Brooks","firstName":"James","href":"http://med.stanford.edu/profiles/cancer/researcher/James_Brooks","researchInterest":"We use genomic approaches to identify disease biomarkers.  We are most interested in translating biomarkers into clinical practice in urological diseases with a particular focus in cancer."},{"lastName":"Arber","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Hematopathology"},{"focus":"Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=3925&type=small&showNoImage","displayName":"Daniel A. Arber, M.D.","firstName":"Daniel","href":"http://med.stanford.edu/profiles/cancer/researcher/Daniel_Arber","researchInterest":"I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/cancer/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/cancer/researcher/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/cancer/researcher/Mickey_Hu","researchInterest":""},{"lastName":"King","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pediatrics - Neonatal and Developmental Medicine"}],"primaryAppointment":"Instructor,Pediatrics - Neonatal and Developmental Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10623&type=small&showNoImage","displayName":"Bonnie King, PhD","firstName":"Bonnie","href":"http://med.stanford.edu/profiles/cancer/researcher/Bonnie_King","researchInterest":"My areas of interest are mammary gland biology and translational breast cancer research. I recently joined the Contag lab as an NIH Career Re-Entry Scientist, where I am using molecular imaging tools to study the process of cancer cell dissemination during breast cancer progression."},{"lastName":"Higgins","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4038&type=small&showNoImage","displayName":"John Higgins","firstName":"John","href":"http://med.stanford.edu/profiles/cancer/researcher/John_Higgins","researchInterest":"I work as a diagnostic surgical pathologist doing translational research in renal neoplasia and medical renal disease and neoplastic and medical liver disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology."},{"lastName":"Jensen","clinicalFocus":[{"focus":"Pathology"},{"focus":"Cytopathology"},{"focus":"Anatomic Pathology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pathology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7660&type=small&showNoImage","displayName":"Kristin Jensen","firstName":"Kristin","href":"http://med.stanford.edu/profiles/cancer/researcher/Kristin_Jensen","researchInterest":"I am a clinical translational investigator with a primary interest in breast cancer biology, and the use of investigational and clinical ancillary techniques such as gene and tissue microarray analysis and immunohistochemistry in the diagnosis and prognosis of this disease. As a practicing cytopathologist, I also have an interest in improving the fine needle aspiration biopsy diagnosis of breast lesions, again using immunohistochemistry and gene expression analysis as adjuncts to cytomorphology."},{"lastName":"Engleman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4490&type=small&showNoImage","displayName":"Edgar Engleman","firstName":"Edgar","href":"http://med.stanford.edu/profiles/cancer/researcher/Edgar_Engleman","researchInterest":"Dendritic cells, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer and autoimmune disease."},{"lastName":"Goodman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - General Medical Disciplines"},{"appointment":"Professor,Health Research & Policy - Epidemiology"}],"primaryAppointment":"Professor,Medicine - General Medical Disciplines","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23410&type=small&showNoImage","displayName":"Steven Goodman","firstName":"Steven","href":"http://med.stanford.edu/profiles/cancer/researcher/Steven_Goodman","researchInterest":"I am interested in issues relating to the representation and measurement of evidence in medical research, and determinants of the truth of medical findings, using a Bayesian framework. I also do work in evidence synthesis, comparative effectiveness research, and the ethics of clinical research. Finally, I have an ongoing project related to landmark clinical trials that have had great impact."},{"lastName":"Duque Afonso","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=29334&type=small&showNoImage","displayName":"Atilio Jesus Duque-Afonso","firstName":"Atilio","href":"http://med.stanford.edu/profiles/postdocs/researcher/Atilio_Duque Afonso","researchInterest":""},{"lastName":"Gonzalgo","clinicalFocus":[{"focus":"Prostate Cancer - Robotic Prostatectomy"},{"focus":"Bladder Cancer - Robotic Cystectomy"},{"focus":"Urologic Oncology - Prostate, Bladder, Kidney, Testicular Cancer"},{"focus":"Urology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Urology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor - Med Center Line,Urology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13213&type=small&showNoImage","displayName":"Mark L. Gonzalgo, M.D., Ph.D.","firstName":"Mark","href":"http://med.stanford.edu/profiles/cancer/researcher/Mark_Gonzalgo","researchInterest":"My laboratory is focused on studying the role of DNA methylation in prostate and bladder cancer.  Certain genes and their downstream targets may be useful molecular markers for disease detection and prognostication. We are interested in utilizing methylation markers to detect abnormal changes in serum and urine.  Clinical Focus: Prostate Cancer - Robotic Prostatectomy; Bladder Cancer - Robotic Cystectomy; Urologic Oncology - Prostate, Bladder, Kidney, Testicular Cancer."},{"lastName":"Sahoo","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10888&type=small&showNoImage","displayName":"Debashis Sahoo","firstName":"Debashis","href":"http://med.stanford.edu/profiles/cancer/researcher/Debashis_Sahoo","researchInterest":""},{"lastName":"Beck","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18189&type=small&showNoImage","displayName":"Andrew Beck","firstName":"Andrew","href":"http://med.stanford.edu/profiles/cancer/researcher/Andrew_Beck","researchInterest":""},{"lastName":"Kenkel","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=19756&type=small&showNoImage","displayName":"Justin Kenkel","firstName":"Justin","href":"http://med.stanford.edu/profiles/cancer/researcher/Justin_Kenkel","researchInterest":""},{"lastName":"Francke","clinicalFocus":[{"focus":"Neurogenetics"},{"focus":"Clinical Genetics"}],"appointments":[{"appointment":"Professor Emeritus,Genetics"},{"appointment":"Emeritus Faculty, Acad Council,Genetics"},{"appointment":"Professor,Pediatrics - Medical Genetics"}],"primaryAppointment":"Professor Emeritus,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","displayName":"Uta Francke","firstName":"Uta","href":"http://med.stanford.edu/profiles/cancer/researcher/Uta_Francke","researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models. Integration of genomic information into medical care."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/cancer/researcher/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Whittemore","clinicalFocus":[],"appointments":[{"appointment":"Professor,Health Research & Policy - Epidemiology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Health Research & Policy - Epidemiology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4482&type=small&showNoImage","displayName":"Alice S Whittemore","firstName":"Alice","href":"http://med.stanford.edu/profiles/cancer/researcher/Alice_Whittemore","researchInterest":"Cancers of the prostate, breast and ovary account for a major proportion of new cancer cases and cancer deaths in the U.S. each year. Our recent research focus has been on developing improved statistical methods for the design and conduct of studies involving hereditary predisposition and modifiable lifestyle characteristics in the etiologies of site-specific cancers."},{"lastName":"Sabatti","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor (By courtesy),Natural Sciences Cluster - Statistics"}],"primaryAppointment":"Associate Professor,Health Research & Policy - Biostatistics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=14357&type=small&showNoImage","displayName":"Chiara Sabatti","firstName":"Chiara","href":"http://med.stanford.edu/profiles/cancer/researcher/Chiara_Sabatti","researchInterest":"Statistical models and reasoning are key to our understanding of the genetic basis of human traits. Modern high-throughput technology presents us with new opportunities and challenges. We develop statistical approaches for high dimensional data in the attempt of improving our understanding of the molecular basis of health related traits."},{"lastName":"Jeffrey","clinicalFocus":[{"focus":"General Surgery"}],"appointments":[{"appointment":"Professor - Med Center Line,Surgery - General Surgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor - Med Center Line,Surgery - General Surgery","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4147&type=small&showNoImage","displayName":"Stefanie S. Jeffrey, MD","firstName":"Stefanie","href":"http://med.stanford.edu/profiles/cancer/researcher/Stefanie_Jeffrey","researchInterest":"Dr. Jeffrey was team leader of the multidisciplinary team from the School of Medicine, School of Engineering, and Genome Technology Center that invented the MagSweeper automated technology to isolate live circulating tumor cells (CTCs) from cancer patient blood for single cell analysis. Her lab characterizes CTCs in different cancers, investigating CTC profiles and mutations as potential companion diagnostics to define individual patient response to newer biologically-based cancer therapies."},{"lastName":"Desai","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Medicine - General Medical Disciplines"},{"appointment":"Associate Professor (Research) (By courtesy),Health Research & Policy"}],"primaryAppointment":"Associate Professor (Research),Medicine - General Medical Disciplines","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13492&type=small&showNoImage","displayName":"Manisha Desai","firstName":"Manisha","href":"http://med.stanford.edu/profiles/cancer/researcher/Manisha_Desai","researchInterest":"Dr. Desai is the Director of the Quantitative Sciences Unit.  She is interested in the application of biostatistical methods to all areas of medicine including oncology, nephrology, and endocrinology.  She works on methods for the analysis of epidemiologic studies, clinical trials, and studies with missing observations."},{"lastName":"Sun","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Urology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4402&type=small&showNoImage","displayName":"Zijie Sun","firstName":"Zijie","href":"http://med.stanford.edu/profiles/cancer/researcher/Zijie_Sun","researchInterest":"My lab focuses on understanding the molecular mechanism of transcription factors that govern the transformation of normal mammalian cells to a neoplastic state. We are especially interested in the action of the nuclear hormone receptors and the interactions between the receptors and other signaling pathways in related human disorders."}]}