{"result":[{"lastName":"Reuter","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=15072&type=small&showNoImage","displayName":"Jason Reuter","firstName":"Jason","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jason_Reuter","researchInterest":""},{"lastName":"Marinkovich","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Autoimmune Blistering Diseases"},{"focus":"Epidermolysis Bullosa"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4217&type=small&showNoImage","displayName":"M. Peter Marinkovich","firstName":"Matt","href":"http://med.stanford.edu/profiles/cancer/researcher/Matt_Marinkovich","researchInterest":"The Marinkovich lab studies the function of epithelial extracellular matrix molecules, including integrins, collagens and laminins in epithelial development and carcinoma progression.  We apply our discoveries in this area towards development of molecular therapies for carcinomas, hair disease and inherited epithelial adhesive disorders."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/cancer/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/cancer/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Lee","clinicalFocus":[{"focus":"Dermatology"},{"focus":"General Dermatology"}],"appointments":[{"appointment":"Clinical Instructor,Dermatology"},{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Clinical Instructor,Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13475&type=small&showNoImage","displayName":"Carolyn Lee","firstName":"Carolyn","href":"http://med.stanford.edu/profiles/cancer/researcher/Carolyn_Lee","researchInterest":""},{"lastName":"Sarin","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Precision Dermatology"},{"focus":"Skin Cancers"},{"focus":"Adverse Drug Reactions"}],"appointments":[{"appointment":"Clinical Assistant Professor,Dermatology"}],"primaryAppointment":"Clinical Assistant Professor,Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=33859&type=small&showNoImage","displayName":"Kavita Sarin","firstName":"Kavita","href":"http://med.stanford.edu/profiles/cancer/researcher/Kavita_Sarin","researchInterest":""},{"lastName":"Flockhart","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Postdoctoral Research fellow, Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=11018&type=small&showNoImage","displayName":"Ross Flockhart","firstName":"Ross","href":"http://med.stanford.edu/profiles/postdocs/researcher/Ross_Flockhart","researchInterest":""},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Bauer","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Dermatology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4177&type=small&showNoImage","displayName":"Eugene Bauer","firstName":"Eugene","href":"http://med.stanford.edu/profiles/cancer/researcher/Eugene_Bauer","researchInterest":"Defining the role of matrix metalloproteinases in connective tissue remodeling of the skin.\u000bDefining the macromolecular structures of the cutaneous basement membrane zone.\u000bDeveloping methods for delivery of extracutaneous gene therapy in epidermolysis bullosa."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/cancer/researcher/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Marques","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=19508&type=small&showNoImage","displayName":"Michelle Marques","firstName":"Michelle","href":"http://med.stanford.edu/profiles/postdocs/researcher/Michelle_Marques","researchInterest":""},{"lastName":"Lorch","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Structural Biology"}],"primaryAppointment":"Associate Professor (Research),Structural Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4116&type=small&showNoImage","displayName":"Yahli Lorch","firstName":"Yahli","href":"http://med.stanford.edu/profiles/cancer/researcher/Yahli_Lorch","researchInterest":""},{"lastName":"Kuo","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=5906&type=small&showNoImage","displayName":"Calvin Kuo","firstName":"Calvin","href":"http://med.stanford.edu/profiles/cancer/researcher/Calvin_Kuo","researchInterest":"We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism.  Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy.  Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells.  We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery."},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/cancer/researcher/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Artandi","clinicalFocus":[{"focus":"Internal Medicine"},{"focus":"General Internal Medicine"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - General Medical Disciplines"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - General Medical Disciplines","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6449&type=small&showNoImage","displayName":"Maja Artandi, MD","firstName":"Maja","href":"http://med.stanford.edu/profiles/cancer/researcher/Maja_Artandi","researchInterest":""},{"lastName":"Sunwoo","clinicalFocus":[{"focus":"Thyroid Neoplasms"},{"focus":"Melanoma"},{"focus":"Parathyroid Neoplasms"},{"focus":"Tongue Neoplasms"},{"focus":"Otolaryngology - Head & Neck Surgery (Ear, Nose and Throat)"},{"focus":"Otolaryngology"},{"focus":"Thyroid Nodule"},{"focus":"Parotid Neoplasms"},{"focus":"Tonsillar Neoplasms"},{"focus":"Pharynx Neoplasms"},{"focus":"Cancer of the Pharynx"},{"focus":"Cancer of the Larynx"},{"focus":"Cancer Stem Cells"},{"focus":"Cancer of Mouth"},{"focus":"Cancer of Neck"},{"focus":"Cancer of the Nasopharynx"},{"focus":"Cancer of Oropharnyx"},{"focus":"Cancer of the Parotid"},{"focus":"Cancer of the Salivary Gland"}],"appointments":[{"appointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8588&type=small&showNoImage","displayName":"John B. Sunwoo","firstName":"John","href":"http://med.stanford.edu/profiles/cancer/researcher/John_Sunwoo","researchInterest":"My laboratory is focused on two primary areas of research: (1) the immune response to head and neck cancer and to a tumorigenic population of cells within these malignancies called cancer stem cells; (2) the developmental programs of a special lymphocyte population involved in innate immunity called natural killer (NK) cells."},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/cancer/researcher/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Cyert","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6213&type=small&showNoImage","displayName":"Martha Cyert","firstName":"Martha","href":"http://med.stanford.edu/profiles/cancer/researcher/Martha_Cyert","researchInterest":"Cells respond to extracellular changes by activating signal transduction pathways, many of which are highly conserved. We study Ca2+-mediated signaling in a simple eukaryote, Saccharomyces cerevisiae. Using genetic, genomic, biochemical and cell biological approaches, we are examining how the Ca2+/calmodulin-regulated phosphatase, calcineurin, regulates gene expression and other cellular processes in response to environmental stress."},{"lastName":"Lee","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Developmental Biology"}],"primaryAppointment":"Basic Life Science Research Associate,Developmental Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=9203&type=small&showNoImage","displayName":"Jonghyeob Lee","firstName":"Jonghyeob","href":"http://cancer.stanford.edu/profiles/Jonghyeob_Lee","researchInterest":""},{"lastName":"Mas Martin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10279&type=small&showNoImage","displayName":"Gloria Mas Martin","firstName":"Gloria","href":"http://med.stanford.edu/profiles/postdocs/researcher/Gloria_Mas Martin","researchInterest":""},{"lastName":"Jackson","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4463&type=small&showNoImage","displayName":"Peter Jackson","firstName":"Peter","href":"http://med.stanford.edu/profiles/cancer/researcher/Peter_Jackson","researchInterest":"Cell cycle and cyclin control of DNA replication ."}]}