{"result":[{"lastName":"Baldwin","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6816&type=small&showNoImage","displayName":"Robert Baldwin","firstName":"Robert","href":"http://med.stanford.edu/profiles/cancer/researcher/Robert_Baldwin","researchInterest":"I closed my laboratory when I retired in 1998.  I continue to do research, chiefly in collaboration with Franc Avbelj, on problems of protein folding energetics, especially peptide backbone solvation,  and to write reviews."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/cancer/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/cancer/researcher/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Doniach","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8062&type=small&showNoImage","displayName":"Sebastian Doniach","firstName":"Sebastian","href":"http://med.stanford.edu/profiles/cancer/researcher/Sebastian_Doniach","researchInterest":""},{"lastName":"Mulholland","clinicalFocus":[],"appointments":[{"appointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine"},{"appointment":"Research & Development Engr,Dean's Office - Center for Molecular and Genetic Medicine"}],"primaryAppointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=26450&type=small&showNoImage","displayName":"Jonathan Mulholland","firstName":"Jonathan","href":"http://cancer.stanford.edu/profiles/Jonathan_Mulholland","researchInterest":""},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/cancer/researcher/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Bryant","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor (By courtesy),Structural Biology"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8004&type=small&showNoImage","displayName":"Zev Bryant","firstName":"Zev","href":"http://med.stanford.edu/profiles/cancer/researcher/Zev_Bryant","researchInterest":"Molecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work."},{"lastName":"Theriot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4432&type=small&showNoImage","displayName":"Julie Theriot","firstName":"Julie","href":"http://med.stanford.edu/profiles/cancer/researcher/Julie_Theriot","researchInterest":"We study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis."},{"lastName":"Straight","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6006&type=small&showNoImage","displayName":"Aaron Straight","firstName":"Aaron","href":"http://med.stanford.edu/profiles/cancer/researcher/Aaron_Straight","researchInterest":"We study the process of cell division. Our research is focused on understanding how chromosomes are segregated during mitosis and how cells divide during cytokinesis."},{"lastName":"Park","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8769&type=small&showNoImage","displayName":"Hyokeun Park","firstName":"Hyokeun","href":"http://med.stanford.edu/profiles/postdocs/researcher/Hyokeun_Park","researchInterest":""},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/cancer/researcher/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Levitt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Computer Science"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4494&type=small&showNoImage","displayName":"Michael Levitt","firstName":"Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/Michael_Levitt","researchInterest":"having pioneered, we (a) predict folding of a polypeptide and RNA chains into a unique native-structure, we (b) model protein structure using the well-established paradigms that similar protein sequences imply similar three-dimensional structures, and (c) we are focusing on mesoscale modeling of large macromolecular complexes such as RNA polymerase and the mammalian chaperonin."},{"lastName":"Teruel","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=14171&type=small&showNoImage","displayName":"Mary Frances Nunez Teruel","firstName":"Mary","href":"http://med.stanford.edu/profiles/cancer/researcher/Mary_Teruel","researchInterest":"The Teruel Lab uses a combination of engineering and biological approaches including high-throughput screening of RNAi and DNA construct libraries, targeted mass spectrometry, live-cell fluorescence microscopy, and bioinformatics to investigate the systems biology of cell differentiation and cell signaling with particular focus on uncovering the molecular mechanisms underlying insulin resistance, diabetes, and obesity."},{"lastName":"Fraser","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=15112&type=small&showNoImage","displayName":"Hunter Fraser","firstName":"Hunter","href":"http://med.stanford.edu/profiles/cancer/researcher/Hunter_Fraser","researchInterest":""},{"lastName":"Pfeffer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4087&type=small&showNoImage","displayName":"Suzanne Pfeffer","firstName":"Suzanne","href":"http://med.stanford.edu/profiles/cancer/researcher/Suzanne_Pfeffer","researchInterest":"The goal of our research is to elucidate the molecular mechanisms by which proteins are targeted to specific membrane compartments. How do transport vesicles select their contents, bud, translocate through the cytoplasm, and then fuse with their targets? We study the Ras-like Rab GTPases--how they serve as master regulators of all receptor trafficking events.  We also study how cells acquire cholesterol from the diet and from LDL."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/cancer/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Weis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Stanford Synchrotron Radiation Lightsource - SSRL"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4259&type=small&showNoImage","displayName":"William Weis","firstName":"William","href":"http://med.stanford.edu/profiles/cancer/researcher/William_Weis","researchInterest":"Our laboratory studies molecular interactions that underlie the establishment and maintenance of cell and tissue structure.  Our specific areas of interest are the architecture and dynamics of intercellular adhesion junctions, the molecular basis of cell polarity, and the Wnt signaling pathway.   We also have a long-standing interest in carbohydrate-based cellular recognition and adhesion."},{"lastName":"Li","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23896&type=small&showNoImage","displayName":"Jingjing Li","firstName":"Jingjing","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jingjing_Li","researchInterest":""},{"lastName":"Cyert","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6213&type=small&showNoImage","displayName":"Martha Cyert","firstName":"Martha","href":"http://med.stanford.edu/profiles/cancer/researcher/Martha_Cyert","researchInterest":"Cells respond to extracellular changes by activating signal transduction pathways, many of which are highly conserved. We study Ca2+-mediated signaling in a simple eukaryote, Saccharomyces cerevisiae. Using genetic, genomic, biochemical and cell biological approaches, we are examining how the Ca2+/calmodulin-regulated phosphatase, calcineurin, regulates gene expression and other cellular processes in response to environmental stress."},{"lastName":"Cao","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=11477&type=small&showNoImage","displayName":"Jian Cao","firstName":"Jian","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jian_Cao","researchInterest":""},{"lastName":"Mallick","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology"}],"primaryAppointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18938&type=small&showNoImage","displayName":"Parag Mallick","firstName":"Parag","href":"http://med.stanford.edu/profiles/cancer/researcher/Parag_Mallick","researchInterest":"Our research centers on developing and applying  proteomics and systems biology approaches to quantitatively describe organisms' physiologic states towards the goal of enabling personalized, predictive medicine.  As part of this effort we are trying to characterize the diverse states of cells (using proteomic and transcriptomic methods) and how signals describing those states are propagated from molecular and cellular length scales to tumor and organismic length scales."},{"lastName":"Tobin","clinicalFocus":[],"appointments":[{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Sr Research Scholar (PI Waiver),Pediatrics - Centers, Center for Biomedical Ethics"}],"primaryAppointment":"Member,Stanford Cancer Institute","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6945&type=small&showNoImage","displayName":"Sara L. (Sally) Tobin","firstName":"Sara","href":"http://med.stanford.edu/profiles/cancer/researcher/Sara_Tobin","researchInterest":"Tobin is a Senior Research Scholar at the Stanford Center for Biomedical Ethics. She obtained her Ph.D. in Developmental Biology from the University of Washington and did postdoctoral research in Genetics at the University of California, Berkeley and in Biochemistry at the University of California, San Francisco. She became a faculty member at the University of Oklahoma College of Medicine in 1983 and moved to Stanford University in 1996. Her research contributions have been published in presti"},{"lastName":"Levy","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor (Research),Medicine - Oncology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","displayName":"Shoshana Levy","firstName":"Shoshana","href":"http://med.stanford.edu/profiles/cancer/researcher/Shoshana_Levy","researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria."}]}