{"result":[{"lastName":"Sibley","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology"}],"appointments":[{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4113&type=small&showNoImage","displayName":"Richard Sibley","firstName":"Richard","href":"http://med.stanford.edu/profiles/cancer/researcher/Richard_Sibley","researchInterest":"Immunologic mechanism of rejection in humans and animal, models of organ transplantation; histological definition of clinical pathology studies of various renal disorders."},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/cancer/researcher/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Kambham","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Renal Pathology"},{"focus":"Anatomic Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=3829&type=small&showNoImage","displayName":"Neeraja Kambham","firstName":"Neeraja","href":"http://med.stanford.edu/profiles/cancer/researcher/Neeraja_Kambham","researchInterest":"Research interests primarily involve medical diseases of the native and transplant kidney. Other interests include liver transplantation pathology and gastrointestinal pathology."},{"lastName":"Parham","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=3998&type=small&showNoImage","displayName":"Peter Parham","firstName":"Peter","href":"http://med.stanford.edu/profiles/cancer/researcher/Peter_Parham","researchInterest":"The Parham laboratory investigates the biology, genetics, and evolution of MHC class I molecules and NK cell receptors."},{"lastName":"Maecker","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Microbiology & Immunology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=25058&type=small&showNoImage","displayName":"Holden Maecker","firstName":"Holden","href":"http://med.stanford.edu/profiles/cancer/researcher/Holden_Maecker","researchInterest":"I'm interested in immune monitoring of T cell responses to chronic pathogens such as CMV, and the correlation of T cell response signatures with disease protection."},{"lastName":"Parnes","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","displayName":"Jane Parnes","firstName":"Jane","href":"http://med.stanford.edu/profiles/cancer/researcher/Jane_Parnes","researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/cancer/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Martinez","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4474&type=small&showNoImage","displayName":"Olivia Martinez","firstName":"Olivia","href":"http://med.stanford.edu/profiles/cancer/researcher/Olivia_Martinez","researchInterest":"EBV B cell lymphomas; pathways of immune evasion in the growth and survival of EBV B cell lymphomas;  mechanisms of graft rejection and tolerance induction; stem cell and solid organ transplantation."},{"lastName":"Krams","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4475&type=small&showNoImage","displayName":"Sheri Krams","firstName":"Sheri","href":"http://med.stanford.edu/profiles/cancer/researcher/Sheri_Krams","researchInterest":"Our recent studies have focused on three specific areas: 1) NK cell interactions with dendritic cells and tumors, 2) MicroRNAs as master regulators in transplantation and viral infections and 3) Mechanisms of tolerance induction."},{"lastName":"Peltz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8527&type=small&showNoImage","displayName":"Gary Peltz","firstName":"Gary","href":"http://med.stanford.edu/profiles/cancer/researcher/Gary_Peltz","researchInterest":"The laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue."},{"lastName":"Grumet","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Pathology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4535&type=small&showNoImage","displayName":"Frank Carl Grumet","firstName":"Frank","href":"http://med.stanford.edu/profiles/cancer/researcher/Frank_Grumet","researchInterest":"Work in our laboratory is focused on the study of the human major histocompatibility (HLA) complex. We are seeking to characterize the genes and gene products of this complex and to understand their role in determining transplantation and transfusion compatibility. Laboratory work on this topic ranges from clinical studies correlating graft rejection with HLA antigens identified by classical serology or DNA typing."},{"lastName":"Michie","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4707&type=small&showNoImage","displayName":"Sara Michie","firstName":"Sara","href":"http://med.stanford.edu/profiles/cancer/researcher/Sara_Michie","researchInterest":"Lymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules."},{"lastName":"Horowitz","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=24057&type=small&showNoImage","displayName":"Amir Horowitz","firstName":"Amir","href":"http://med.stanford.edu/profiles/postdocs/researcher/Amir_Horowitz","researchInterest":""},{"lastName":"Higgins","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4038&type=small&showNoImage","displayName":"John Higgins","firstName":"John","href":"http://med.stanford.edu/profiles/cancer/researcher/John_Higgins","researchInterest":"I work as a diagnostic surgical pathologist doing translational research in renal neoplasia and medical renal disease and neoplastic and medical liver disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology."},{"lastName":"Chan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"Postdoctoral Medical fellow, Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23335&type=small&showNoImage","displayName":"Steven Chan","firstName":"Steven","href":"http://med.stanford.edu/profiles/postdocs/researcher/Steven_Chan","researchInterest":""},{"lastName":"Grimm","clinicalFocus":[{"focus":"Pediatric Nephrology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Nephrology"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Nephrology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7989&type=small&showNoImage","displayName":"Paul C. Grimm","firstName":"Paul","href":"http://med.stanford.edu/profiles/cancer/researcher/Paul_Grimm","researchInterest":"Computerized image analysis of kidney and liver biopsies to quantitate and diagnose subtle changes in tissue structure. \r\nRenal Inflammation\r\nRenal Allograft Rejection\r\nRenal Fibrosis in; \r\n-Primary Kidney Disease\r\n-Transplant Kidney Disease\r\nLiver fibrosis\r\nSteatohepatitis"},{"lastName":"Rouse","clinicalFocus":[],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4491&type=small&showNoImage","displayName":"Robert V Rouse","firstName":"Robert","href":"http://med.stanford.edu/profiles/cancer/researcher/Robert_Rouse","researchInterest":"My recent research efforts are currently focused in the field of applications of immunohistology to the diagnosis of human neoplasms. This work is predominantly aimed at characterizing markers for the identification of non-lymphoid neoplasms and at establishing criteria for their evaluation in diagnostic situations."},{"lastName":"Bonham","clinicalFocus":[{"focus":"General Surgery"},{"focus":"Liver Transplantation"},{"focus":"Live-donor Liver Transplantation"},{"focus":"Pediatric Transplantation"},{"focus":"Intestinal Transplantation"},{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Portal Hypertension"},{"focus":"Hepatobiliary Surgery"},{"focus":"Cancer of Biliary Tract"},{"focus":"Cancer, Liver"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=3884&type=small&showNoImage","displayName":"Clark Bonham","firstName":"Clark","href":"http://med.stanford.edu/profiles/cancer/researcher/Clark_Bonham","researchInterest":"Tolerance induction in liver transplantation.\r\nHepatocyte transplantation."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/cancer/researcher/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Thauland","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=33300&type=small&showNoImage","displayName":"Timothy Thauland","firstName":"Timothy","href":"http://med.stanford.edu/profiles/postdocs/researcher/Timothy_Thauland","researchInterest":""},{"lastName":"Rosen","clinicalFocus":[{"focus":"Pulmonology (Lung) and Critical Care "},{"focus":"Pulmonary Disease"}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4245&type=small&showNoImage","displayName":"Glenn Rosen","firstName":"Glenn","href":"http://med.stanford.edu/profiles/cancer/researcher/Glenn_Rosen","researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung.  We are also studying signaling pathways that regulate cancer cell growth and metastasis."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/cancer/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/cancer/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Warnke","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Emeritus (Active) Professor,Pathology"},{"appointment":"Emeritus Faculty, Acad Council,Pathology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Emeritus (Active) Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=3786&type=small&showNoImage","displayName":"Roger Warnke","firstName":"Roger","href":"http://med.stanford.edu/profiles/cancer/researcher/Roger_Warnke","researchInterest":"The research in my laboratory involves the application of monoclonal and polyclonal antibodies and a variety of immunohistochemical methods to study human B-cell, T-cell, accessory cell and related neoplasms."}]}