{"result":[{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/cancer/researcher/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Michie","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4707&type=small&showNoImage","displayName":"Sara Michie","firstName":"Sara","href":"http://med.stanford.edu/profiles/cancer/researcher/Sara_Michie","researchInterest":"Lymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules."},{"lastName":"Chan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"Postdoctoral Medical fellow, Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23335&type=small&showNoImage","displayName":"Steven Chan","firstName":"Steven","href":"http://med.stanford.edu/profiles/postdocs/researcher/Steven_Chan","researchInterest":""},{"lastName":"Utz","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4001&type=small&showNoImage","displayName":"Paul Utz","firstName":"Paul","href":"http://med.stanford.edu/profiles/cancer/researcher/Paul_Utz","researchInterest":"The long-term research goal of Dr. Utz\u0092s laboratory is (1) to develop a better understanding of the pathogenic mechanisms underlying systemic lupus erythematosus (SLE) and other autoimmune diseases by exploring signaling pathways that are activated during apoptosis; and (2) to better understand the complicated process of programmed cell death."},{"lastName":"Peltz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8527&type=small&showNoImage","displayName":"Gary Peltz","firstName":"Gary","href":"http://med.stanford.edu/profiles/cancer/researcher/Gary_Peltz","researchInterest":"The laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue."},{"lastName":"Maecker","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Microbiology & Immunology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=25058&type=small&showNoImage","displayName":"Holden Maecker","firstName":"Holden","href":"http://med.stanford.edu/profiles/cancer/researcher/Holden_Maecker","researchInterest":"I'm interested in immune monitoring of T cell responses to chronic pathogens such as CMV, and the correlation of T cell response signatures with disease protection."},{"lastName":"Kodama","clinicalFocus":[],"appointments":[{"appointment":"Engr Res Assoc,Pediatrics - Systems Medicine"}],"primaryAppointment":"Engr Res Assoc,Pediatrics - Systems Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=27436&type=small&showNoImage","displayName":"Keiichi Kodama","firstName":"Keiichi","href":"http://cancer.stanford.edu/profiles/Keiichi_Kodama","researchInterest":""},{"lastName":"Parnes","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","displayName":"Jane Parnes","firstName":"Jane","href":"http://med.stanford.edu/profiles/cancer/researcher/Jane_Parnes","researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease."},{"lastName":"Yip","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Instructor,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=9220&type=small&showNoImage","displayName":"Linda Yip","firstName":"Linda","href":"http://med.stanford.edu/profiles/cancer/researcher/Linda_Yip","researchInterest":""},{"lastName":"Goronzy","clinicalFocus":[{"focus":"Vasculitis"},{"focus":"Rheumatoid Arthritis"},{"focus":"Immunology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=15394&type=small&showNoImage","displayName":"Jorg Goronzy","firstName":"Jorg","href":"http://med.stanford.edu/profiles/cancer/researcher/Jorg_Goronzy","researchInterest":""},{"lastName":"Weyand","clinicalFocus":[{"focus":"Immunology"},{"focus":"Vasculitis"},{"focus":"Rheumatoid Arthritis"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=15618&type=small&showNoImage","displayName":"Cornelia Weyand","firstName":"Cornelia","href":"http://med.stanford.edu/profiles/cancer/researcher/Cornelia_Weyand","researchInterest":""},{"lastName":"Wren","clinicalFocus":[{"focus":"Surgical Oncology"},{"focus":"Colorectal Surgery"},{"focus":"General Surgery"},{"focus":"Surgical Procedures, Minimally Invasive"},{"focus":"Robotics"}],"appointments":[{"appointment":"Professor - Med Center Line,Surgery - General Surgery"}],"primaryAppointment":"Professor - Med Center Line,Surgery - General Surgery","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4440&type=small&showNoImage","displayName":"Sherry M. Wren","firstName":"Sherry","href":"http://med.stanford.edu/profiles/cancer/researcher/Sherry_Wren","researchInterest":"Our research interests are primarily in surgical oncology, especially gastrointestinal cancers. We are also developing new research studies in surgical outcomes."},{"lastName":"Martinez","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4474&type=small&showNoImage","displayName":"Olivia Martinez","firstName":"Olivia","href":"http://med.stanford.edu/profiles/cancer/researcher/Olivia_Martinez","researchInterest":"EBV B cell lymphomas; pathways of immune evasion in the growth and survival of EBV B cell lymphomas;  mechanisms of graft rejection and tolerance induction; stem cell and solid organ transplantation."},{"lastName":"Bonham","clinicalFocus":[{"focus":"General Surgery"},{"focus":"Liver Transplantation"},{"focus":"Live-donor Liver Transplantation"},{"focus":"Pediatric Transplantation"},{"focus":"Intestinal Transplantation"},{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Portal Hypertension"},{"focus":"Hepatobiliary Surgery"},{"focus":"Cancer of Biliary Tract"},{"focus":"Cancer, Liver"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=3884&type=small&showNoImage","displayName":"Clark Bonham","firstName":"Clark","href":"http://med.stanford.edu/profiles/cancer/researcher/Clark_Bonham","researchInterest":"Tolerance induction in liver transplantation.\r\nHepatocyte transplantation."},{"lastName":"Lau","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=30657&type=small&showNoImage","displayName":"Audrey Lau","firstName":"Audrey","href":"http://med.stanford.edu/profiles/postdocs/researcher/Audrey_Lau","researchInterest":""},{"lastName":"Krams","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4475&type=small&showNoImage","displayName":"Sheri Krams","firstName":"Sheri","href":"http://med.stanford.edu/profiles/cancer/researcher/Sheri_Krams","researchInterest":"Our recent studies have focused on three specific areas: 1) NK cell interactions with dendritic cells and tumors, 2) MicroRNAs as master regulators in transplantation and viral infections and 3) Mechanisms of tolerance induction."},{"lastName":"Sibley","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology"}],"appointments":[{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4113&type=small&showNoImage","displayName":"Richard Sibley","firstName":"Richard","href":"http://med.stanford.edu/profiles/cancer/researcher/Richard_Sibley","researchInterest":"Immunologic mechanism of rejection in humans and animal, models of organ transplantation; histological definition of clinical pathology studies of various renal disorders."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=29437&type=small&showNoImage","displayName":"Everett Meyer","firstName":"Everett","href":"http://med.stanford.edu/profiles/postdocs/researcher/Everett_Meyer","researchInterest":""},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13753&type=small&showNoImage","displayName":"Jun Huang","firstName":"Jun","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jun_Huang","researchInterest":""},{"lastName":"Negrin","clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Hematology"}],"appointments":[{"appointment":"Professor,Medicine - Blood & Marrow Transplantation"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Blood & Marrow Transplantation","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4138&type=small&showNoImage","displayName":"Robert Negrin","firstName":"Robert","href":"http://med.stanford.edu/profiles/cancer/researcher/Robert_Negrin","researchInterest":"Our labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells."},{"lastName":"Steinman","clinicalFocus":[{"focus":"Neurology"},{"focus":"Neurology, Pediatric"},{"focus":"Multiple Sclerosis, Myasthenia Gravis, Immune Disorders"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=3784&type=small&showNoImage","displayName":"Lawrence Steinman","firstName":"Lawrence","href":"http://med.stanford.edu/profiles/cancer/researcher/Lawrence_Steinman","researchInterest":"Our laboratory is dedicated to understanding the pathogenesis of autoimmune diseases, particularly multiple sclerosis.  We have developed several new therapies for autoimmunity, including some in Phase 2 clinical trials, as well as one approved drug, natalizumab.  We have developed microarray technology for detecting autoantibodies to myelin proteins and lipids.  We employ a diverse range of molecular and celluar approaches to trying to understand multiple sclerosis."}]}