{"result":[{"lastName":"Einav","clinicalFocus":[{"focus":"Infectious Disease"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Infectious Diseases"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Assistant Professor,Microbiology & Immunology"}],"primaryAppointment":"Assistant Professor,Medicine - Infectious Diseases","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=9992&type=small&showNoImage","displayName":"Shirit Einav","firstName":"Shirit","href":"http://med.stanford.edu/profiles/cancer/researcher/Shirit_Einav","researchInterest":"My lab focuses on better understanding virus-host protein-protein interactions. We combine novel proteomic approaches, including high-fidelity microfluidics platforms, with molecular virology, biochemical, and functional genomic approaches for identification of host partners conservatively required by various viruses and development of broad-spectrum antiviral strategies with a high genetic barrier for resistance. We focus on Flaviviridae (currently, hepatitis C (HCV) and dengue) as well as HIV"},{"lastName":"Sarnow","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4458&type=small&showNoImage","displayName":"Peter Sarnow","firstName":"Peter","href":"http://med.stanford.edu/profiles/cancer/researcher/Peter_Sarnow","researchInterest":"Our laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated."},{"lastName":"Fire","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Professor,Genetics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=3989&type=small&showNoImage","displayName":"Andrew Fire","firstName":"Andrew","href":"http://med.stanford.edu/profiles/cancer/researcher/Andrew_Fire","researchInterest":"We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as \"self\" versus \"nonself\" or \"wanted\" versus \"unwanted\"."},{"lastName":"Glenn","clinicalFocus":[{"focus":"Gastroenterology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Microbiology & Immunology"}],"primaryAppointment":"Associate Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4576&type=small&showNoImage","displayName":"Jeffrey S.  Glenn, M.D., Ph.D.","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/cancer/researcher/Jeffrey_Glenn","researchInterest":"Dr. Glenn's primary interest is in molecular virology, with a strong emphasis on translating this knowledge into novel antiviral therapies. Other interests include exploitation of hepatic stem cells, engineered human liver tissues, and new biodefense antiviral strategies."},{"lastName":"Cao","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Pediatrics - Human Gene Therapy"},{"appointment":"Life Science Research Asst,Anesthesia"}],"primaryAppointment":"Basic Life Science Research Associate,Pediatrics - Human Gene Therapy","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=9557&type=small&showNoImage","displayName":"Dan Cao","firstName":"Dan","href":"http://cancer.stanford.edu/profiles/Dan_Cao","researchInterest":""},{"lastName":"Lan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13653&type=small&showNoImage","displayName":"Feng Lan","firstName":"Feng","href":"http://med.stanford.edu/profiles/postdocs/researcher/Feng_Lan","researchInterest":""},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Calos","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4100&type=small&showNoImage","displayName":"Michele Calos","firstName":"Michele","href":"http://med.stanford.edu/profiles/cancer/researcher/Michele_Calos","researchInterest":"My lab is developing innovative gene and cell therapies for genetic diseases, with a focus on stem cell therapies and regenerative medicine.  \r\n\r\nWe have created novel methods for inserting therapeutic genes into the chromosomes at specific places by using homologous recombination and recombinase enzymes.   \r\n\r\nWe are working on two forms of muscular dystrophy.  \r\n\r\nWe created induced pluripotent stem cells from patient fibroblasts, added therapeutic genes, differentiated, and engrafted the cells."},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/cancer/researcher/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/cancer/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Sheikh","clinicalFocus":[{"focus":"Cardiothoracic Surgery and Transplantation"},{"focus":"Mechanical Circulatory Support"},{"focus":"General Surgery"}],"appointments":[{"appointment":"Clinical Instructor,Cardiothoracic Surgery - Adult Cardiac Surgery"}],"primaryAppointment":"Clinical Instructor,Cardiothoracic Surgery - Adult Cardiac Surgery","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=35536&type=small&showNoImage","displayName":"Ahmad Sheikh","firstName":"Ahmad","href":"http://med.stanford.edu/profiles/cancer/researcher/Ahmad_Sheikh","researchInterest":"Molecular imaging of cardiac stem cell therapy\r\nHeart failure\r\nCardiothoracic Transplantation\r\nSurgical Education"},{"lastName":"Paulmurugan","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=14774&type=small&showNoImage","displayName":"Ramasamy Paulmurugan","firstName":"Ramasamy","href":"http://med.stanford.edu/profiles/cancer/researcher/Ramasamy_Paulmurugan","researchInterest":""},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/cancer/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Connolly","clinicalFocus":[{"focus":"Anatomic Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6324&type=small&showNoImage","displayName":"Andrew J. Connolly","firstName":"Andrew","href":"http://med.stanford.edu/profiles/cancer/researcher/Andrew_Connolly","researchInterest":"My research interests are vascular biology and cardiovascular pathology.  We are currently working on gene expression in endothelial cells at sites of pathology."},{"lastName":"Zheng","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Postdoctoral Research fellow, Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=19342&type=small&showNoImage","displayName":"Grace Zheng","firstName":"Xinying","href":"http://med.stanford.edu/profiles/postdocs/researcher/Xinying_Zheng","researchInterest":""},{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://med.stanford.edu/profiles/cancer/researcher/Arend_Sidow","researchInterest":"We are interested in the systems biology of molecular phenotypes, and how genetic variation affects them. The lab combines experimental approaches in developing mouse embryos as well as human cancers with computational analyses. Our main data engine is high-throughput sequencing. Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Li","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18946&type=small&showNoImage","displayName":"Jin Billy Li","firstName":"Jin","href":"http://med.stanford.edu/profiles/cancer/researcher/Jin_Li","researchInterest":""},{"lastName":"Urban","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Psychiatry & Behavioral Science - Psychopharmacology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor (By courtesy),Genetics"}],"primaryAppointment":"Assistant Professor,Psychiatry & Behavioral Science - Psychopharmacology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18259&type=small&showNoImage","displayName":"Alexander Urban","firstName":"Alexander","href":"http://med.stanford.edu/profiles/cancer/researcher/Alexander_Urban","researchInterest":""},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23069&type=small&showNoImage","displayName":"Shenglin Huang","firstName":"Shenglin","href":"http://med.stanford.edu/profiles/postdocs/researcher/Shenglin_Huang","researchInterest":""},{"lastName":"Cleary","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4506&type=small&showNoImage","displayName":"Michael Cleary","firstName":"Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/Michael_Cleary","researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/cancer/researcher/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Chu","clinicalFocus":[{"focus":"Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Biochemistry"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4149&type=small&showNoImage","displayName":"Gilbert Chu","firstName":"Gilbert","href":"http://med.stanford.edu/profiles/cancer/researcher/Gilbert_Chu","researchInterest":"Our laboratory focuses on understanding how cells respond to DNA damage. Our research currently involves areas that interact with each other: repair of radiation damage, and transcriptional responses to DNA damage."},{"lastName":"Campbell","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6212&type=small&showNoImage","displayName":"Allan Campbell","firstName":"Allan","href":"http://med.stanford.edu/profiles/cancer/researcher/Allan_Campbell","researchInterest":""},{"lastName":"Moayeri","clinicalFocus":[{"focus":"Pathology Clinical"}],"appointments":[{"appointment":"Clinical Assistant Professor,Pathology"}],"primaryAppointment":"Clinical Assistant Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=36934&type=small&showNoImage","displayName":"Morvarid Moayeri","firstName":"Morvarid","href":"http://med.stanford.edu/profiles/cancer/researcher/Morvarid_Moayeri","researchInterest":""}]}