{"result":[{"lastName":"Peehl","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Urology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor (Research),Urology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4633&type=small&showNoImage","displayName":"Donna Peehl, PhD","firstName":"Donna","href":"http://med.stanford.edu/profiles/cancer/researcher/Donna_Peehl","researchInterest":"My research focuses on the molecular and cellular biology of the human prostate. Developing realistic experimental models is a major goal, and primary cultures of prostatic epithelial and stromal cells are my main model system. Our discoveries are relevant to prevention, detection, diagnosis and treatment of benign and malignant prostatic diseases."},{"lastName":"Wang","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18632&type=small&showNoImage","displayName":"Jennifer Wang","firstName":"Jennifer","href":"http://med.stanford.edu/profiles/cancer/researcher/Jennifer_Wang","researchInterest":""},{"lastName":"Faig","clinicalFocus":[{"focus":"Obstetrics and Gynecology"},{"focus":"Endocrinopathies in Pregnancy"},{"focus":"Thyroid Disease in Pregnancy"},{"focus":"Diabetes in Pregnancy"}],"appointments":[{"appointment":"Clinical Professor,Obstetrics & Gynecology - Maternal Fetal Medicine"}],"primaryAppointment":"Clinical Professor,Obstetrics & Gynecology - Maternal Fetal Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4031&type=small&showNoImage","displayName":"Jeffrey Clayton Faig, MD, FACOG, FACP","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/cancer/researcher/Jeffrey_Faig","researchInterest":""},{"lastName":"Sun","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Urology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4402&type=small&showNoImage","displayName":"Zijie Sun","firstName":"Zijie","href":"http://med.stanford.edu/profiles/cancer/researcher/Zijie_Sun","researchInterest":"My lab focuses on understanding the molecular mechanism of transcription factors that govern the transformation of normal mammalian cells to a neoplastic state. We are especially interested in the action of the nuclear hormone receptors and the interactions between the receptors and other signaling pathways in related human disorders."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/cancer/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Albertelli","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Comparative Medicine"}],"primaryAppointment":"Assistant Professor - Med Center Line,Comparative Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=11414&type=small&showNoImage","displayName":"Megan Albertelli","firstName":"Megan","href":"http://med.stanford.edu/profiles/cancer/researcher/Megan_Albertelli","researchInterest":""},{"lastName":"Brooks","clinicalFocus":[{"focus":"Male Cancers - Prostate "},{"focus":"Prostate Cancer"},{"focus":"Nerve-sparing radical prostatectomy"},{"focus":"Prostate Cancer - Urologic Oncology"},{"focus":"Urologic Cancers"},{"focus":"Urologic Cancers - Urologic Oncology"},{"focus":"Urology"}],"appointments":[{"appointment":"Professor,Urology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Urology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6178&type=small&showNoImage","displayName":"James D. Brooks","firstName":"James","href":"http://med.stanford.edu/profiles/cancer/researcher/James_Brooks","researchInterest":"We use genomic approaches to identify disease biomarkers.  We are most interested in translating biomarkers into clinical practice in urological diseases with a particular focus in cancer."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/cancer/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Desai","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Medicine - General Medical Disciplines"},{"appointment":"Associate Professor (Research) (By courtesy),Health Research & Policy"}],"primaryAppointment":"Associate Professor (Research),Medicine - General Medical Disciplines","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13492&type=small&showNoImage","displayName":"Manisha Desai","firstName":"Manisha","href":"http://med.stanford.edu/profiles/cancer/researcher/Manisha_Desai","researchInterest":"Dr. Desai is the Director of the Quantitative Sciences Unit.  She is interested in the application of biostatistical methods to all areas of medicine including oncology, nephrology, and endocrinology.  She works on methods for the analysis of epidemiologic studies, clinical trials, and studies with missing observations."},{"lastName":"Jensen","clinicalFocus":[{"focus":"Pathology"},{"focus":"Cytopathology"},{"focus":"Anatomic Pathology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pathology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7660&type=small&showNoImage","displayName":"Kristin Jensen","firstName":"Kristin","href":"http://med.stanford.edu/profiles/cancer/researcher/Kristin_Jensen","researchInterest":"I am a clinical translational investigator with a primary interest in breast cancer biology, and the use of investigational and clinical ancillary techniques such as gene and tissue microarray analysis and immunohistochemistry in the diagnosis and prognosis of this disease. As a practicing cytopathologist, I also have an interest in improving the fine needle aspiration biopsy diagnosis of breast lesions, again using immunohistochemistry and gene expression analysis as adjuncts to cytomorphology."},{"lastName":"Gardner","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Medicine - Stanford Prevention Research Center"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor (Research),Medicine - Stanford Prevention Research Center","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4085&type=small&showNoImage","displayName":"Christopher Gardner","firstName":"Christopher","href":"http://med.stanford.edu/profiles/cancer/researcher/Christopher_Gardner","researchInterest":"The role of nutrition in individual and societal health, with particular interests in: plant-based diets, differential response to low-carb vs. low-fat weight loss diets by insulin resistance status, chronic disease prevention, randomized controlled trials, human nutrition, community based studies, Community Based Participatory Research, sustainable food movement (animal rights and welfare, global warming, human labor practices), stealth health, nutrition policy, nutrition guidelines"},{"lastName":"Lin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Orthopaedic Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Orthopaedic Surgery","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=38115&type=small&showNoImage","displayName":"Tzu-hua Lin","firstName":"Tzu-hua","href":"http://med.stanford.edu/profiles/postdocs/researcher/Tzu-hua_Lin","researchInterest":""},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/cancer/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Hanawalt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Dermatology"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=5957&type=small&showNoImage","displayName":"Philip C. Hanawalt","firstName":"Philip","href":"http://med.stanford.edu/profiles/cancer/researcher/Philip_Hanawalt","researchInterest":"Our current research focuses in two principal areas:\r\n\r\n1. The molecular basis for  diseases in which the pathway of transcription-coupled DNA repair is defective, including Cockyne syndrome (CS) and UV-sensitive syndrome (UVSS). Patients are severely sensitive to sunlight  but  get no cancers. See Hanawalt & Spivak, 2008, for review.\r\n\r\n2. Transcription arrest by guanine-rich DNA sequences and non-canonical secondary structures. Transcription collisions with replication forks."},{"lastName":"Wilson","clinicalFocus":[{"focus":"Endocrinology/Diabetes, Pediatric"},{"focus":"Pediatric Endocrinology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Endocrinology and Diabetes"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Endocrinology and Diabetes","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4182&type=small&showNoImage","displayName":"Darrell Wilson","firstName":"Darrell","href":"http://med.stanford.edu/profiles/cancer/researcher/Darrell_Wilson","researchInterest":"My research interests cover a number of areas in Pediatric Endocrinology and Diabetes. I am PI of the Stanford Center for the NIH-funded Type-1 Diabetes TrialNet group. TrialNet conducts clinical trials directed at preventing or delaying the onset of Type 1 diabetes. I am an investigator in DirecNet, another NIH-funded study group, which is devoted to evaluating glucose sensors and the role of technology on the management of diabetes."},{"lastName":"Rabkin","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Nephrology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Nephrology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6052&type=small&showNoImage","displayName":"Ralph Rabkin","firstName":"Ralph","href":"http://med.stanford.edu/profiles/cancer/researcher/Ralph_Rabkin","researchInterest":"Dr Rabkin is examining the mechanism of the acquired resistance to hormones that develops in kidney failure.In particular he is studying the impact of kidney failure on the action of growth hormone and the role of impaired signal transduction as a cause of growth hormone resistance. He is also engaged in the study of growth factors in diabetic kidney disease."},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"West","clinicalFocus":[],"appointments":[{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Stanford Cancer Institute","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6327&type=small&showNoImage","displayName":"Dee W. West","firstName":"Dee","href":"http://med.stanford.edu/profiles/cancer/researcher/Dee_West","researchInterest":"- Cancer etiology (diet, familial, genetic), especially breast, prostate and colon cancer\r\n- Cancer surveillance (Cancer registration, cancer patterns)\r\n- Cancer outcomes (Survival, quality of life, quality of care)"},{"lastName":"Longo","clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","displayName":"Frank M. Longo, M.D., Ph.D.","firstName":"Frank","href":"http://med.stanford.edu/profiles/cancer/researcher/Frank_Longo","researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders."},{"lastName":"Horn-Ross","clinicalFocus":[],"appointments":[{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Stanford Cancer Institute","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7424&type=small&showNoImage","displayName":"Pamela Horn-Ross","firstName":"Pamela","href":"http://med.stanford.edu/profiles/cancer/researcher/Pamela_Horn-Ross","researchInterest":"My research interests focus on nutrition and the etiology of hormonally-dependent cancers in women (most particularly breast, endometrial, and thyroid cancers).  Of particular interest are the effects of phytochemicals that may reduce cancer risk, such as the isoflavones in soy foods, the lignans in whole grains, the isothiocyanates in broccoli and other cruciferous vegetables, and resveratrol in red wine and peanuts. Nutrient-gene interactions are also of interest."},{"lastName":"van de Rijn","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Sarcoma"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4008&type=small&showNoImage","displayName":"Matt van de Rijn","firstName":"Matt","href":"http://med.stanford.edu/profiles/cancer/researcher/Matt_van de Rijn","researchInterest":"Our research focuses on gene microarray analysis of human soft tissue tumors (sarcomas). In addition we work with tissue microarrays to characterize large numbers of novel antisera raised against peptides derived from genes found to be of interest during gene array analysis."},{"lastName":"Rosen","clinicalFocus":[{"focus":"Pulmonology (Lung) and Critical Care "},{"focus":"Pulmonary Disease"}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4245&type=small&showNoImage","displayName":"Glenn Rosen","firstName":"Glenn","href":"http://med.stanford.edu/profiles/cancer/researcher/Glenn_Rosen","researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung.  We are also studying signaling pathways that regulate cancer cell growth and metastasis."},{"lastName":"Roth","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4175&type=small&showNoImage","displayName":"Richard Roth","firstName":"Richard","href":"http://med.stanford.edu/profiles/cancer/researcher/Richard_Roth","researchInterest":"Insulin is one of the primary regulators of rapid anabolic responses in the body. Defects in the synthesis and/or ability of cells to respond to insulin results in the condition known as diabetes mellitus. To better design methods of treatment for this disorder, we have been focusing our research on how insulin elicits its various biological responses."},{"lastName":"Peltz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8527&type=small&showNoImage","displayName":"Gary Peltz","firstName":"Gary","href":"http://med.stanford.edu/profiles/cancer/researcher/Gary_Peltz","researchInterest":"The laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue."},{"lastName":"Lu","clinicalFocus":[],"appointments":[{"appointment":"Professor,Health Research & Policy - Biostatistics"}],"primaryAppointment":"Professor,Health Research & Policy - Biostatistics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=14526&type=small&showNoImage","displayName":"Ying Lu","firstName":"Ying","href":"http://med.stanford.edu/profiles/cancer/researcher/Ying_Lu","researchInterest":"Biostatistics, clinical trials, statistical evaluation of medical diagnostic tests, radiology, osteoporosis, meta-analysis, medical decisoin making"}]}