{"result":[{"lastName":"Samos","clinicalFocus":[],"appointments":[{"appointment":"Science Writer/Editor,Neurosurgery"},{"appointment":"Information Editor,Neurosurgery"}],"primaryAppointment":"Science Writer/Editor,Neurosurgery","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=28093&type=small&showNoImage","displayName":"Cynthia Samos","firstName":"Cynthia","href":"http://cancer.stanford.edu/profiles/Cynthia_Samos","researchInterest":""},{"lastName":"Krasnow","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4120&type=small&showNoImage","displayName":"Mark Krasnow","firstName":"Mark","href":"http://med.stanford.edu/profiles/cancer/researcher/Mark_Krasnow","researchInterest":"- Lung development and stem cells\r\n- Neural control of breathing\r\n- Lung diseases including lung cancer\r\n- New genetic model organisms for medicine"},{"lastName":"Sylvester","clinicalFocus":[{"focus":"Surgery, Pediatric"},{"focus":"Pediatric Surgery"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor - Med Center Line,Pediatrics"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=3827&type=small&showNoImage","displayName":"Karl Sylvester","firstName":"Karl","href":"http://med.stanford.edu/profiles/cancer/researcher/Karl_Sylvester","researchInterest":"Current research interests include mesenchymal stem cell biology, clonal isolation of mesenchymal progenitors, signaling pathways for maintenance of potency and committment to differentiation.\r\n\r\nAdditional areas of ongoing study are the mechanisms of liver regeneration. Interests include local and humoral cellular components of liver repair and regrowth; and the requisite cellular signaling mechanisms of liver stem cell biology."},{"lastName":"Baker","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6206&type=small&showNoImage","displayName":"Bruce Baker","firstName":"Bruce","href":"http://med.stanford.edu/profiles/cancer/researcher/Bruce_Baker","researchInterest":""},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/cancer/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Olivares","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18321&type=small&showNoImage","displayName":"Gonzalo Olivares","firstName":"Gonzalo","href":"http://med.stanford.edu/profiles/postdocs/researcher/Gonzalo_Olivares","researchInterest":"Stem cells are unique in that can renew themselves through cell division or differentiate into a diverse range of specialized cell types. I will study genes that functions to prevent the growth of tumors and regulates stem cell decisions. Understanding the molecular mechanisms that mediate the choice between self-renewal and differentiation in stem cells has important implications for many areas of biology, including ancer treatment, regenerative medicine and new cell-based therapies."},{"lastName":"Axelrod","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4410&type=small&showNoImage","displayName":"Jeffrey Axelrod","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/cancer/researcher/Jeffrey_Axelrod","researchInterest":"Genetic and cell biological analyses of signals controlling cell polarity and morphogenesis. Frizzled signaling and cytoskeletal organization."},{"lastName":"Kuo","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=5906&type=small&showNoImage","displayName":"Calvin Kuo","firstName":"Calvin","href":"http://med.stanford.edu/profiles/cancer/researcher/Calvin_Kuo","researchInterest":"We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism. Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy. Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells. We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery."},{"lastName":"Ruiz-Lozano","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Pediatrics - Cardiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Pediatrics - Cardiology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18359&type=small&showNoImage","displayName":"Pilar Ruiz-Lozano, Ph.D.","firstName":"Pilar","href":"http://med.stanford.edu/profiles/cancer/researcher/Pilar_Ruiz-Lozano","researchInterest":"Cardiac development and repair"},{"lastName":"Chang","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6387&type=small&showNoImage","displayName":"Ching-Pin Chang","firstName":"Ching-Pin","href":"http://med.stanford.edu/profiles/cancer/researcher/Ching-Pin_Chang","researchInterest":"The ultimate goal of my laboratory is to define the molecular mechanisms underlying cardiovascular development and disease and translate the bench findings to clinical applications. One objective is to understand how the major types of cardiac cells (endocardial, myocardial, epicardial and neural crest cells) interact with each other to generate heart tissues. We are interested in chromatin regulation, transcriptional and signaling events that coordinate their interactions and assembly into hea"},{"lastName":"Cheng","clinicalFocus":[{"focus":"Otolaryngology"},{"focus":"Hearing loss"},{"focus":"Cholesteotoma"},{"focus":"Pediatric sinus disease"},{"focus":"Pediatric head and neck tumors"}],"appointments":[{"appointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Assistant Professor (By courtesy),Pediatrics"}],"primaryAppointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8272&type=small&showNoImage","displayName":"Alan G. Cheng","firstName":"Alan","href":"http://med.stanford.edu/profiles/cancer/researcher/Alan_Cheng","researchInterest":"Active Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated. Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage."},{"lastName":"Chai","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13792&type=small&showNoImage","displayName":"Renjie Chai","firstName":"Renjie","href":"http://med.stanford.edu/profiles/postdocs/researcher/Renjie_Chai","researchInterest":""},{"lastName":"Habib","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Developmental Biology"}],"primaryAppointment":"Basic Life Science Research Associate,Developmental Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=9590&type=small&showNoImage","displayName":"Shukry Habib","firstName":"Shukry","href":"http://cancer.stanford.edu/profiles/Shukry_Habib","researchInterest":"Can External Cues Induce Asymmetric Division of Stem cells?"},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/cancer/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks. This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Ge","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=21246&type=small&showNoImage","displayName":"Xuecai Ge","firstName":"Xuecai","href":"http://med.stanford.edu/profiles/postdocs/researcher/Xuecai_Ge","researchInterest":"I am interested in how the Hedgehog signaling transduction is regulated, and how the mis-regulation of Hedgehog pathway leads to human diseases such as Medulloblastoma."},{"lastName":"Chang","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=17967&type=small&showNoImage","displayName":"Woody Chang","firstName":"Woody","href":"http://med.stanford.edu/profiles/cancer/researcher/Woody_Chang","researchInterest":"A comparative study of the ethical issues in regards to the laetrile controversy of the 1970s and the experimental stem cell tourism controversy of the 2000s. Starting a new project on comparing international reporting of stem cell research between English speaking regions."},{"lastName":"Francke","clinicalFocus":[{"focus":"Neurogenetics"},{"focus":"Clinical Genetics"}],"appointments":[{"appointment":"Professor Emeritus,Genetics"},{"appointment":"Emeritus Faculty, Acad Council,Genetics"},{"appointment":"Professor,Pediatrics - Medical Genetics"}],"primaryAppointment":"Professor Emeritus,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","displayName":"Uta Francke","firstName":"Uta","href":"http://med.stanford.edu/profiles/cancer/researcher/Uta_Francke","researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models. Integration of genomic information into medical care."},{"lastName":"Harel","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=37895&type=small&showNoImage","displayName":"Itamar Harel","firstName":"Itamar","href":"http://med.stanford.edu/profiles/postdocs/researcher/Itamar_Harel","researchInterest":"The overarching goal of the Brunet lab is to understand the genetic mechanisms of aging and longevity. Aging is a highly plastic process regulated by a combination of genetic and environmental factors. \r\n\r\nI am interested in the basic molecular components that characterize \u0093young\u0094 and \u0093aged\u0094 cellular states. Aging is associated with an increased onset of cancer, and I seeks to define the set of factors that can rejuvenate an aged cell, without the risk of malignant transformation. Ultimately, w"},{"lastName":"van de Rijn","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Sarcoma"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4008&type=small&showNoImage","displayName":"Matt van de Rijn","firstName":"Matt","href":"http://med.stanford.edu/profiles/cancer/researcher/Matt_van de Rijn","researchInterest":"Our research focuses on gene microarray analysis of human soft tissue tumors (sarcomas). In addition we work with tissue microarrays to characterize large numbers of novel antisera raised against peptides derived from genes found to be of interest during gene array analysis."},{"lastName":"Okada","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Neurology & Neurological Sciences"}],"primaryAppointment":"Instructor,Neurology & Neurological Sciences","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8191&type=small&showNoImage","displayName":"Ami Okada","firstName":"Ami","href":"http://med.stanford.edu/profiles/cancer/researcher/Ami_Okada","researchInterest":"Our interests are to understand the mechanism and control of signals that regulate proliferation and differentiation in adult tissue. We are currently focused on studying modulation of the Hedgehog pathway in brain and muscle stem cell compartments during normal homeostasis and in degeneration or disease."}]}