{"result":[{"lastName":"Ferrell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Biochemistry"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4656&type=small&showNoImage","displayName":"James Ferrell","firstName":"James","href":"http://med.stanford.edu/profiles/cancer/researcher/James_Ferrell","researchInterest":"My lab has two main goals: to understand mitotic regulation and to understand the systems-level logic of simple signaling circuits.  We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study.  We also carry out single-cell fluorescence imaging studies on mammalian cell lines.  Our experimental work is complemented by computational and theoretical studies aimed at identifying the design principles of regulatory circuits."},{"lastName":"Theriot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4432&type=small&showNoImage","displayName":"Julie Theriot","firstName":"Julie","href":"http://med.stanford.edu/profiles/cancer/researcher/Julie_Theriot","researchInterest":"We study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis."},{"lastName":"Levy","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor (Research),Medicine - Oncology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","displayName":"Shoshana Levy","firstName":"Shoshana","href":"http://med.stanford.edu/profiles/cancer/researcher/Shoshana_Levy","researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/cancer/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Chandra","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=29038&type=small&showNoImage","displayName":"Anchal Chandra","firstName":"Anchal","href":"http://med.stanford.edu/profiles/postdocs/researcher/Anchal_Chandra","researchInterest":""},{"lastName":"Jackson","clinicalFocus":[],"appointments":[{"appointment":"Acting Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Acting Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4463&type=small&showNoImage","displayName":"Peter Jackson","firstName":"Peter","href":"http://med.stanford.edu/profiles/cancer/researcher/Peter_Jackson","researchInterest":"Cell cycle and cyclin control of DNA replication ."},{"lastName":"Cao","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=11477&type=small&showNoImage","displayName":"Jian Cao","firstName":"Jian","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jian_Cao","researchInterest":""},{"lastName":"McGhee","clinicalFocus":[{"focus":"Allergy and Immunology"},{"focus":"Aspirin Desensitization"},{"focus":"Asthma"},{"focus":"DiGeorge Syndrome"},{"focus":"Food Allergies"},{"focus":"Primary Immunodeficiency Diseases"},{"focus":"22q11 Deletion Syndrome"}],"appointments":[{"appointment":"Clinical Assistant Professor,Pediatrics - Immunology and Allergy"}],"primaryAppointment":"Clinical Assistant Professor,Pediatrics - Immunology and Allergy","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=21077&type=small&showNoImage","displayName":"Sean McGhee","firstName":"Sean","href":"http://med.stanford.edu/profiles/cancer/researcher/Sean_McGhee","researchInterest":"Bioinformatics"},{"lastName":"Epel","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6218&type=small&showNoImage","displayName":"David Epel","firstName":"David","href":"http://med.stanford.edu/profiles/cancer/researcher/David_Epel","researchInterest":""},{"lastName":"Yan","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Hematology"}],"primaryAppointment":"Instructor,Medicine - Hematology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13412&type=small&showNoImage","displayName":"Kelley Yan","firstName":"Kelley","href":"http://med.stanford.edu/profiles/cancer/researcher/Kelley_Yan","researchInterest":""},{"lastName":"Green","clinicalFocus":[],"appointments":[{"appointment":"Professor - Med Center Line,Comparative Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor - Med Center Line,Comparative Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4470&type=small&showNoImage","displayName":"Sherril L. Green, DVM, PhD","firstName":"Sherril","href":"http://med.stanford.edu/profiles/cancer/researcher/Sherril_Green","researchInterest":"Research Interests: Xenopus laevis. Husbandry, biology, infectious and parasitic diseases of laboratory Xenopus laevis. Large animal models of disease."},{"lastName":"Goyos","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18147&type=small&showNoImage","displayName":"Ana Goyos","firstName":"Ana","href":"http://med.stanford.edu/profiles/postdocs/researcher/Ana_Goyos","researchInterest":""},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/cancer/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Pfeffer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4087&type=small&showNoImage","displayName":"Suzanne Pfeffer","firstName":"Suzanne","href":"http://med.stanford.edu/profiles/cancer/researcher/Suzanne_Pfeffer","researchInterest":"The goal of our research is to elucidate the molecular mechanisms by which proteins are targeted to specific membrane compartments. How do transport vesicles select their contents, bud, translocate through the cytoplasm, and then fuse with their targets? We study the Ras-like Rab GTPases--how they serve as master regulators of all receptor trafficking events.  We also study how cells acquire cholesterol from the diet and from LDL."},{"lastName":"Nishikii","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=38377&type=small&showNoImage","displayName":"Hidekazu NIshikii","firstName":"Hidekazu","href":"http://med.stanford.edu/profiles/postdocs/researcher/Hidekazu_Nishikii","researchInterest":""},{"lastName":"Olivares","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=18321&type=small&showNoImage","displayName":"Gonzalo Olivares","firstName":"Gonzalo","href":"http://med.stanford.edu/profiles/postdocs/researcher/Gonzalo_Olivares","researchInterest":"Stem cells are unique in that can renew themselves through cell division or differentiate into a diverse range of specialized cell types.  I will study genes that functions to prevent the growth of tumors and regulates stem cell decisions. Understanding the molecular mechanisms that mediate the choice between self-renewal and differentiation in stem cells has important implications for many areas of biology, including ancer treatment, regenerative medicine and new cell-based therapies."},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/cancer/researcher/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"Straight","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6006&type=small&showNoImage","displayName":"Aaron Straight","firstName":"Aaron","href":"http://med.stanford.edu/profiles/cancer/researcher/Aaron_Straight","researchInterest":"We study the process of cell division. Our research is focused on understanding how chromosomes are segregated during mitosis and how cells divide during cytokinesis."},{"lastName":"Kurzer","clinicalFocus":[{"focus":"Hematopathology"}],"appointments":[{"appointment":"Instructor,Pathology"}],"primaryAppointment":"Instructor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23643&type=small&showNoImage","displayName":"Jason Kurzer","firstName":"Jason","href":"http://med.stanford.edu/profiles/cancer/researcher/Jason_Kurzer","researchInterest":""},{"lastName":"Roth","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4175&type=small&showNoImage","displayName":"Richard Roth","firstName":"Richard","href":"http://med.stanford.edu/profiles/cancer/researcher/Richard_Roth","researchInterest":"Insulin is one of the primary regulators of rapid anabolic responses in the body. Defects in the synthesis and/or ability of cells to respond to insulin results in the condition known as diabetes mellitus. To better design methods of treatment for this disorder, we have been focusing our research on how insulin elicits its various biological responses."},{"lastName":"Mall","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stem Cell"}],"primaryAppointment":"Postdoctoral Research fellow, Stem Cell","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=34619&type=small&showNoImage","displayName":"Moritz Mall","firstName":"Moritz","href":"http://med.stanford.edu/profiles/postdocs/researcher/Moritz_Mall","researchInterest":""},{"lastName":"Lowe","clinicalFocus":[{"focus":"Gastroenterology"},{"focus":"Pancreatic diseases"}],"appointments":[{"appointment":"Associate Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Associate Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4184&type=small&showNoImage","displayName":"Anson Lowe","firstName":"Anson","href":"http://med.stanford.edu/profiles/cancer/researcher/Anson_Lowe","researchInterest":"Our laboratory is focused on the development of adenocarcinomas, which are cancers of glandular tissues. Active projects are focused on pancreatic, esophageal, colon, and lung adenocarcinomas. Our work addresses the cause, diagnosis, and treatment of adenocarcinomas."}]}