{"result":[{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Cherry","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4249&type=small&showNoImage","displayName":"Mike Cherry","firstName":"J. Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/J. Michael_Cherry","researchInterest":"My research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education.  Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments.  The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research."},{"lastName":"Li","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23896&type=small&showNoImage","displayName":"Jingjing Li","firstName":"Jingjing","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jingjing_Li","researchInterest":""},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/cancer/researcher/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Collins","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10605&type=small&showNoImage","displayName":"Sean Collins","firstName":"Sean","href":"http://med.stanford.edu/profiles/postdocs/researcher/Sean_Collins","researchInterest":""},{"lastName":"Montgomery","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor,Genetics"},{"appointment":"Assistant Professor (By courtesy),Computer Science"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23650&type=small&showNoImage","displayName":"Stephen B. Montgomery","firstName":"Stephen","href":"http://med.stanford.edu/profiles/cancer/researcher/Stephen_Montgomery","researchInterest":"We focus on understanding the effects of genome variation on cellular phenotypes and cellular modeling of disease through genomic approaches such as next generation RNA sequencing in combination with developing and utilizing state-of-the-art bioinformatics and statistical genetics approaches.  See our website at http://montgomerylab.stanford.edu/"},{"lastName":"Kelley","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=19462&type=small&showNoImage","displayName":"Joanna Kelley","firstName":"Joanna","href":"http://med.stanford.edu/profiles/postdocs/researcher/Joanna_Kelley","researchInterest":""},{"lastName":"Sherlock","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=5864&type=small&showNoImage","displayName":"Gavin Sherlock","firstName":"Gavin","href":"http://med.stanford.edu/profiles/cancer/researcher/Gavin_Sherlock","researchInterest":"Evolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species"},{"lastName":"Mas Martin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10279&type=small&showNoImage","displayName":"Gloria Mas Martin","firstName":"Gloria","href":"http://med.stanford.edu/profiles/postdocs/researcher/Gloria_Mas Martin","researchInterest":""},{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://med.stanford.edu/profiles/cancer/researcher/Arend_Sidow","researchInterest":"We are interested in the systems biology of molecular phenotypes, and how genetic variation affects them. The lab combines experimental approaches in developing mouse embryos as well as human cancers with computational analyses. Our main data engine is high-throughput sequencing. Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Roskin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=21093&type=small&showNoImage","displayName":"Krishna Roskin","firstName":"Krishna","href":"http://med.stanford.edu/profiles/postdocs/researcher/Krishna_Roskin","researchInterest":""},{"lastName":"Wei","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Biochemistry - Stanford Genome Technology Center"}],"primaryAppointment":"Basic Life Science Research Associate,Biochemistry - Stanford Genome Technology Center","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=29094&type=small&showNoImage","displayName":"Wu Wei","firstName":"Wu","href":"http://cancer.stanford.edu/profiles/Wu_Wei","researchInterest":""},{"lastName":"Owen","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=8072&type=small&showNoImage","displayName":"Art Owen","firstName":"Art","href":"http://med.stanford.edu/profiles/cancer/researcher/Art_Owen","researchInterest":""},{"lastName":"Haimovich","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=21024&type=small&showNoImage","displayName":"Ariel Haimovich","firstName":"Ariel","href":"http://med.stanford.edu/profiles/postdocs/researcher/Ariel_Haimovich","researchInterest":""},{"lastName":"Chua","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Medicine - Endocrinology, Gerontology, & Metabolism"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Medicine - Endocrinology, Gerontology, & Metabolism","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6623&type=small&showNoImage","displayName":"Katrin Chua","firstName":"Katrin","href":"http://med.stanford.edu/profiles/cancer/researcher/Katrin_Chua","researchInterest":"Our lab is interested in understanding molecular processes that underlie aging and age-associated pathologies in mammals.  We focus on a family of genes, the SIRTs, which regulate stress resistance and lifespan in lower organisms such as yeast, worms, and flies.  In mammals, we recently uncovered a number of ways in which SIRT factors may contribute to cellular and organismal aging by regulating resistance to various forms of stress.  We have now begun to characterize the molecular mechanisms b"},{"lastName":"Cyert","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6213&type=small&showNoImage","displayName":"Martha Cyert","firstName":"Martha","href":"http://med.stanford.edu/profiles/cancer/researcher/Martha_Cyert","researchInterest":"Cells respond to extracellular changes by activating signal transduction pathways, many of which are highly conserved. We study Ca2+-mediated signaling in a simple eukaryote, Saccharomyces cerevisiae. Using genetic, genomic, biochemical and cell biological approaches, we are examining how the Ca2+/calmodulin-regulated phosphatase, calcineurin, regulates gene expression and other cellular processes in response to environmental stress."},{"lastName":"Cornejo","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=17162&type=small&showNoImage","displayName":"Omar Eduardo Cornejo Ordaz","firstName":"Omar","href":"http://med.stanford.edu/profiles/postdocs/researcher/Omar_Cornejo","researchInterest":"I am mainly interested in understanding the relative roles of recombination, mutation and selection in shaping genetic variation in and determining the genetic structure of populations of microorganism, especially those that are etiological agents of infectious diseases.   I am also interested in disentangling the contribution of forces generating and maintaining variation genome wide and the use of new technologies for the assessment of variation in different organisms."},{"lastName":"Mulholland","clinicalFocus":[],"appointments":[{"appointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine"},{"appointment":"Research & Development Engr,Dean's Office - Center for Molecular and Genetic Medicine"}],"primaryAppointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=26450&type=small&showNoImage","displayName":"Jonathan Mulholland","firstName":"Jonathan","href":"http://cancer.stanford.edu/profiles/Jonathan_Mulholland","researchInterest":""},{"lastName":"Sabatti","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor (By courtesy),Natural Sciences Cluster - Statistics"}],"primaryAppointment":"Associate Professor,Health Research & Policy - Biostatistics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=14357&type=small&showNoImage","displayName":"Chiara Sabatti","firstName":"Chiara","href":"http://med.stanford.edu/profiles/cancer/researcher/Chiara_Sabatti","researchInterest":"Statistical models and reasoning are key to our understanding of the genetic basis of human traits. Modern high-throughput technology presents us with new opportunities and challenges. We develop statistical approaches for high dimensional data in the attempt of improving our understanding of the molecular basis of health related traits."},{"lastName":"Song","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=34618&type=small&showNoImage","displayName":"Giltae Song","firstName":"Gil Tae","href":"http://med.stanford.edu/profiles/postdocs/researcher/Gil Tae_Song","researchInterest":""},{"lastName":"Skotheim","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor (By courtesy),Chemical and Systems Biology"},{"appointment":" (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10452&type=small&showNoImage","displayName":"Jan Skotheim","firstName":"Jan","href":"http://med.stanford.edu/profiles/cancer/researcher/Jan_Skotheim","researchInterest":"A central aim of the burgeoning field of systems biology is to understand the principles governing genetic control networks. I believe finding the principles underlying genetic circuits will occur through detailed studies and then comparisons of several natural systems. Due to its extensive development as an experimental system, our favorite model, the budding yeast cell cycle, is poised to become central to this enterprise."},{"lastName":"Davis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Genetics"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","displayName":"Ronald W. Davis","firstName":"Ronald","href":"http://med.stanford.edu/profiles/cancer/researcher/Ronald_Davis","researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion."}]}