{"result":[{"lastName":"Collins","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10605&type=small&showNoImage","displayName":"Sean Collins","firstName":"Sean","href":"http://med.stanford.edu/profiles/postdocs/researcher/Sean_Collins","researchInterest":""},{"lastName":"Libuda","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10498&type=small&showNoImage","displayName":"Diana Libuda","firstName":"Diana","href":"http://med.stanford.edu/profiles/postdocs/researcher/Diana_Libuda","researchInterest":"My research aims to understand how chromosomes interact to maintain genomic integrity and promote proper chromosome segregation.  Recombination between chromosomes is required to generate genetic variation, maintain genome integrity through the repair of DNA breaks, and ensure proper chromosome segregation during meiosis, the specialized cell division program by which diploid organisms generate haploid gametes.  Perturbations in recombination events can compromise these basic cellular functions"},{"lastName":"Hargreaves","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=14395&type=small&showNoImage","displayName":"Diana Hargreaves","firstName":"Diana","href":"http://med.stanford.edu/profiles/postdocs/researcher/Diana_Hargreaves","researchInterest":""},{"lastName":"Lorch","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Structural Biology"}],"primaryAppointment":"Associate Professor (Research),Structural Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4116&type=small&showNoImage","displayName":"Yahli Lorch","firstName":"Yahli","href":"http://med.stanford.edu/profiles/cancer/researcher/Yahli_Lorch","researchInterest":""},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Mas Martin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=10279&type=small&showNoImage","displayName":"Gloria Mas Martin","firstName":"Gloria","href":"http://med.stanford.edu/profiles/postdocs/researcher/Gloria_Mas Martin","researchInterest":""},{"lastName":"Kuo","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=19506&type=small&showNoImage","displayName":"Alex J. Kuo","firstName":"Jen-Hao","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jen-Hao_Kuo","researchInterest":""},{"lastName":"Cyert","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6213&type=small&showNoImage","displayName":"Martha Cyert","firstName":"Martha","href":"http://med.stanford.edu/profiles/cancer/researcher/Martha_Cyert","researchInterest":"Cells respond to extracellular changes by activating signal transduction pathways, many of which are highly conserved. We study Ca2+-mediated signaling in a simple eukaryote, Saccharomyces cerevisiae. Using genetic, genomic, biochemical and cell biological approaches, we are examining how the Ca2+/calmodulin-regulated phosphatase, calcineurin, regulates gene expression and other cellular processes in response to environmental stress."},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/cancer/researcher/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Haimovich","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=21024&type=small&showNoImage","displayName":"Ariel Haimovich","firstName":"Ariel","href":"http://med.stanford.edu/profiles/postdocs/researcher/Ariel_Haimovich","researchInterest":""},{"lastName":"Hanawalt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Dermatology"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=5957&type=small&showNoImage","displayName":"Philip C. Hanawalt","firstName":"Philip","href":"http://med.stanford.edu/profiles/cancer/researcher/Philip_Hanawalt","researchInterest":"Our current research focuses in two principal areas:\r\n\r\n1. The molecular basis for  diseases in which the pathway of transcription-coupled DNA repair is defective, including Cockyne syndrome (CS) and UV-sensitive syndrome (UVSS). Patients are severely sensitive to sunlight  but  get no cancers. See Hanawalt & Spivak, 2008, for review.\r\n\r\n2. Transcription arrest by guanine-rich DNA sequences and non-canonical secondary structures. Transcription collisions with replication forks."},{"lastName":"Mulholland","clinicalFocus":[],"appointments":[{"appointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine"},{"appointment":"Research & Development Engr,Dean's Office - Center for Molecular and Genetic Medicine"}],"primaryAppointment":"Director, CSIF,Dean's Office - Center for Molecular and Genetic Medicine","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=26450&type=small&showNoImage","displayName":"Jonathan Mulholland","firstName":"Jonathan","href":"http://cancer.stanford.edu/profiles/Jonathan_Mulholland","researchInterest":""},{"lastName":"Cherry","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4249&type=small&showNoImage","displayName":"Mike Cherry","firstName":"J. Michael","href":"http://med.stanford.edu/profiles/cancer/researcher/J. Michael_Cherry","researchInterest":"My research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education.  Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments.  The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research."},{"lastName":"Chang","clinicalFocus":[{"focus":"Dermatology"},{"focus":"General Dermatology"}],"appointments":[{"appointment":"Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Dermatology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","displayName":"Howard Y. Chang","firstName":"Howard","href":"http://med.stanford.edu/profiles/cancer/researcher/Howard_Chang","researchInterest":"Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods  have provided insights into human development, cancer, and aging."},{"lastName":"Chu","clinicalFocus":[{"focus":"Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Biochemistry"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=4149&type=small&showNoImage","displayName":"Gilbert Chu","firstName":"Gilbert","href":"http://med.stanford.edu/profiles/cancer/researcher/Gilbert_Chu","researchInterest":"Our laboratory focuses on understanding how cells respond to DNA damage. Our research currently involves areas that interact with each other: repair of radiation damage, and transcriptional responses to DNA damage."},{"lastName":"Bua","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=19834&type=small&showNoImage","displayName":"Dennis J Bua","firstName":"Dennis","href":"http://med.stanford.edu/profiles/postdocs/researcher/Dennis_Bua","researchInterest":""},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/cancer/researcher/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Li","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=23896&type=small&showNoImage","displayName":"Jingjing Li","firstName":"Jingjing","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jingjing_Li","researchInterest":""},{"lastName":"Fraser","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=15112&type=small&showNoImage","displayName":"Hunter Fraser","firstName":"Hunter","href":"http://med.stanford.edu/profiles/cancer/researcher/Hunter_Fraser","researchInterest":""},{"lastName":"Sherlock","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Genetics","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=5864&type=small&showNoImage","displayName":"Gavin Sherlock","firstName":"Gavin","href":"http://med.stanford.edu/profiles/cancer/researcher/Gavin_Sherlock","researchInterest":"Evolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species"},{"lastName":"Wysocka","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Associate Professor,Developmental Biology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://cancer.stanford.edu/profiles/viewImage?facultyId=7764&type=small&showNoImage","displayName":"Joanna Wysocka","firstName":"Joanna","href":"http://med.stanford.edu/profiles/cancer/researcher/Joanna_Wysocka","researchInterest":"Research in our lab focuses on mechanisms of epigenetic regulation in differentiation and development. In particular, we are studying the function of histone modifying enzymes in embryonic stem cell self-renewal and in early cell fate decisions. We are interested in the role of chromatin modifications in establishment and maintenance of gene expression patterns during normal and pathological development, and in nuclear reprogramming."}]}