Cancer Institute A national cancer institute
designated cancer center

Atul Butte

Publication Details

  • Translational bioinformatics in the cloud: an affordable alternative. Genome medicine Dudley, J. T., Pouliot, Y., Chen, R., Morgan, A. A., Butte, A. J. 2010; 2 (8): 51-?


    With the continued exponential expansion of publicly available genomic data and access to low-cost, high-throughput molecular technologies for profiling patient populations, computational technologies and informatics are becoming vital considerations in genomic medicine. Although cloud computing technology is being heralded as a key enabling technology for the future of genomic research, available case studies are limited to applications in the domain of high-throughput sequence data analysis. The goal of this study was to evaluate the computational and economic characteristics of cloud computing in performing a large-scale data integration and analysis representative of research problems in genomic medicine. We find that the cloud-based analysis compares favorably in both performance and cost in comparison to a local computational cluster, suggesting that cloud computing technologies might be a viable resource for facilitating large-scale translational research in genomic medicine.

    View details for DOI 10.1186/gm172

    View details for PubMedID 20691073

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