Cancer Institute A national cancer institute
designated cancer center

Atul Butte

Publication Details

  • Likelihood ratios for genome medicine. Genome medicine Morgan, A. A., Chen, R., Butte, A. J. 2010; 2 (5): 30-?


    Patients are beginning to present to healthcare providers with the results of high-throughput individualized genotyping, and interpreting these results in the context of the explosive growth of literature linking individual variants with disease may seem daunting. However, we suggest that results of a personal genomic analysis may be viewed as a panel of many tests for multiple diseases. By using well-established methods of evidence based medicine, these very many parallel tests may be combined using likelihood ratios to report a post-test probability of disease for use in patient assessment.

    View details for DOI 10.1186/gm151

    View details for PubMedID 20497613

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