Edward Graves
Publication Details
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Hypoxia in models of lung cancer: implications for targeted therapeutics.
Clin Cancer Res. 2010; (19): 4843-52
To efficiently translate experimental methods from bench to bedside, it is imperative that laboratory models of cancer mimic human disease as closely as possible. In this study, we sought to compare patterns of hypoxia in several standard and emerging mouse models of lung cancer to establish the appropriateness of each for evaluating the role of oxygen in lung cancer progression and therapeutic response.
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