Joseph DiCarlo
Publication Details
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Effect of exogenous surfactant (calfactant) in pediatric acute lung injury: a randomized controlled trial.
JAMA. 2005; (4): 470-6
Despite evidence that patients with acute lung injury (ALI) have pulmonary surfactant dysfunction, trials of several surfactant preparations to treat adults with ALI have not been successful. Preliminary studies in children with ALI have shown that instillation of a natural lung surfactant (calfactant) containing high levels of surfactant-specific protein B may be beneficial.

