Cancer Institute A national cancer institute
designated cancer center

Jeffrey Axelrod

Publication Details

  • PROLINE-INDEPENDENT BINDING OF PUT3 TRANSCRIPTIONAL ACTIVATOR PROTEIN DETECTED BY FOOTPRINTING INVIVO MOLECULAR AND CELLULAR BIOLOGY Axelrod, J. D., Majors, J., Brandriss, M. C. 1991; 11 (1): 564-567

    Abstract:

    The PUT3 gene product is a transcriptional activator required for expression of the enzymes of the proline utilization pathway. Using two methods of footprinting in vivo, we have determined that PUT3 protein is poised at the promoters of the genes encoding these enzymes and that proline-mediated induction modulates the activity of constitutively bound PUT3.

    View details for Web of Science ID A1991ER08100060

    View details for PubMedID 1986247

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