Cancer Institute A national cancer institute
designated cancer center

Jeffrey Axelrod

Publication Details

  • Dishevelled links basal body docking and orientation in ciliated epithelial cells TRENDS IN CELL BIOLOGY Vladar, E. K., Axelrod, J. D. 2008; 18 (11): 517-520


    Some epithelia contain cells with multiple motile cilia that beat in a concerted manner. New tools and experimental systems have facilitated molecular studies of cilium biogenesis and the coordinated planar polarization of cilia that leads to their concerted motility. A recent elegant study using embryonic frog epidermis demonstrates that Dishevelled, a key regulator of both the Wnt-beta-catenin and planar cell polarity pathways, controls both the docking and planar polarization of ciliary basal bodies.

    View details for DOI 10.1016/j.tcb.2008.08.004

    View details for Web of Science ID 000261074400001

    View details for PubMedID 18819800

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