Cancer Institute A national cancer institute
designated cancer center

Stefanie S. Jeffrey, MD

Publication Details

  • Cell trapping in activated micropores for functional analysis. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference Talasaz, A. H., Powell, A. A., Stahl, P., Ronaghi, M., Jeffrey, S. S., Mindrinos, M., Davis, R. W. 2006; 1: 1838-1841


    This paper presents a novel device which provides the opportunity to perform high-throughput biochemical assays on different individual cells. In particular, the proposed device is suited to screen the rare cells in biological samples for early stage cancer diagnosis and explore their biochemical functionality. In the process, single cells are precisely positioned and captured in activated micropores. To show the performance of the proposed device, cultured yeast cells and human epithelial circulating tumor cells are successfully captured.

    View details for PubMedID 17945673

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