Cancer Institute A national cancer institute
designated cancer center

Stefanie S. Jeffrey, MD

Publication Details

  • Transcriptomic signatures in breast cancer MOLECULAR BIOSYSTEMS Fu, J., Jeffrey, S. S. 2007; 3 (7): 466-472


    High throughput DNA microarray technology has been broadly applied to the study of breast cancer to classify molecular subtypes, to predict outcome, survival, response to treatment, and for the identification of novel therapeutic targets. Although results are promising, this technology will not have a full impact on routine clinical practice until there is further standardization of techniques and optimal clinical trial design. Due to substantial disease heterogeneity and the number of genes being analyzed, collaborative, multi-institutional studies are required to accrue enough patients for sufficient statistical power. Newer bioinformatic approaches are being developed to assist with the analysis of this important data.

    View details for DOI 10.1039/b618163e

    View details for Web of Science ID 000247397700003

    View details for PubMedID 17579771

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