Cancer Institute A national cancer institute
designated cancer center

Jeffrey Axelrod

Publication Details

  • Biology by numbers: mathematical modelling in developmental biology NATURE REVIEWS GENETICS Tomlin, C. J., Axelrod, J. D. 2007; 8 (5): 331-340


    In recent years, mathematical modelling of developmental processes has earned new respect. Not only have mathematical models been used to validate hypotheses made from experimental data, but designing and testing these models has led to testable experimental predictions. There are now impressive cases in which mathematical models have provided fresh insight into biological systems, by suggesting, for example, how connections between local interactions among system components relate to their wider biological effects. By examining three developmental processes and corresponding mathematical models, this Review addresses the potential of mathematical modelling to help understand development.

    View details for DOI 10.1038/nrg2098

    View details for Web of Science ID 000245906500013

    View details for PubMedID 17440530

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