Cancer Institute A national cancer institute
designated cancer center

Philip W. Lavori

Publication Details

  • Adding an alcohol-related risk score to an existing categorical risk classification for older adults: Sensitivity to group differences JOURNAL OF THE AMERICAN GERIATRICS SOCIETY Wilson, S. R., Fink, A., Verghese, S., Beck, J. C., Nguyen, K., Lavori, P. 2007; 55 (3): 445-450

    Abstract:

    To evaluate a new alcohol-related risk score for research use.Using data from a previously reported trial of a screening and education system for older adults (Computerized Alcohol-Related Problems Survey), secondary analyses were conducted comparing the ability of two different measures of risk to detect post-intervention group differences: the original categorical outcome measure and a new, finely grained quantitative risk score based on the same research-based risk factors.Three primary care group practices in southern California.Six hundred sixty-five patients aged 65 and older.A previously calculated, three-level categorical classification of alcohol-related risk and a newly developed quantitative risk score.Mean post-intervention risk scores differed between the three experimental conditions: usual care, patient report, and combined report (P<.001). The difference between the combined report and usual care was significant (P<.001) and directly proportional to baseline risk. The three-level risk classification did not reveal approximately 57.3% of the intervention effect detected by the risk score. The risk score also was sufficiently sensitive to detect the intervention effect within the subset of hypertensive patients (n=112; P=.001).As an outcome measure in intervention trials, the finely grained risk score is more sensitive than the trinary risk classification. The additional clinical value of the risk score relative to the categorical measure needs to be determined.

    View details for DOI 10.1111/j.1532-5415.2007.01072.x

    View details for Web of Science ID 000244519400019

    View details for PubMedID 17341250

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