Cancer Institute A national cancer institute
designated cancer center

Matthew Bogyo

Publication Details

  • A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I cathepsin C JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Yuan, F., Verhelst, S. H., Blum, G., Coussens, L. M., Bogyo, M. 2006; 128 (17): 5616-5617


    Dipeptidyl peptidase I is involved in the activation of a number of disease-related proteases by removal of N-terminal prodipeptides. We here report a selective activity-based probe for monitoring dipeptidyl peptidase I activity in whole proteomes as well as in intact cells, without labeling of closely related enzyme family members.

    View details for DOI 10.1021/ja060835v

    View details for Web of Science ID 000237389900014

    View details for PubMedID 16637611

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