Cancer Institute A national cancer institute
designated cancer center

Ronald Levy, MD

Publication Details

  • Intratumoral Anti-CTLA-4 Therapy: Enhancing Efficacy While Avoiding Toxicity CLINICAL CANCER RESEARCH Marabelle, A., Kohrt, H., Levy, R. 2013; 19 (19): 5261-5263

    Abstract:

    Systemic administration of the checkpoint blockade antibody anti-CTLA4 results in severe autoimmune toxicity, limiting its clinical efficacy. Fransen and colleagues show here that peritumoral delivery of low doses of this immunomodulatory drug can trigger a systemic antitumor immune response while preventing the toxicity against other organs.

    View details for DOI 10.1158/1078-0432.CCR-13-1923

    View details for Web of Science ID 000325203700001

    View details for PubMedID 23965900

Stanford Medicine Resources:

Footer Links: