Cancer Institute A national cancer institute
designated cancer center

Jeffrey Axelrod

Publication Details

  • A second canon: Functions and mechanisms of beta-catenin-independent wnt signaling DEVELOPMENTAL CELL Veeman, M. T., Axelrod, J. D., Moon, R. T. 2003; 5 (3): 367-377


    More is becoming known about so-called noncanonical Wnt pathways that signal independently of beta-catenin. Here we review recent developments in both the functions and mechanisms of noncanonical Wnt signaling. We also discuss some unresolved and vexing questions. How many noncanonical Wnt pathways are there? How extensive are the parallels between Drosophila planar polarization and vertebrate convergence and extension? Last, we will outline some challenges and difficulties we foresee for this exciting but still very young field.

    View details for Web of Science ID 000185309600006

    View details for PubMedID 12967557

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