Cancer Institute A national cancer institute
designated cancer center

James L. Zehnder, M.D.

Publication Details

  • Use of the polymerase chain reaction in the evaluation of cutaneous T-cell infiltrates DERMATOLOGIC CLINICS Kohler, S., Zehnder, J. L. 1999; 17 (3): 657-?


    Histologic evaluation of suspected cutaneous T-cell neoplasia is challenging. There is significant overlap with features of benign condition, and neoplastic cells often occur in a reactive background. Recently, molecular techniques using paraffin-embedded tissue have been applied to the diagnosis of cutaneous T-cell infiltrates. These methods are useful for determining whether a clonal population of T-cells is present. The advantages and limitation of molecular diagnostic methods in the diagnosis of cutaneous T-cell infiltrates are discussed.

    View details for Web of Science ID 000081318700015

    View details for PubMedID 10410865

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