Cancer Institute A national cancer institute
designated cancer center

Dean W. Felsher

Publication Details

  • Cancer revoked: oncogenes as therapeutic targets NATURE REVIEWS CANCER Felsher, D. W. 2003; 3 (5): 375-380

    Abstract:

    Recent findings show that even the brief inactivation of a single oncogene might be sufficient to result in the sustained loss of a neoplastic phenotype. It is therefore possible that the targeted inactivation of oncogenes could be a specific and effective treatment for cancer. So why does oncogene inactivation cause tumour regression and will this be a generally successful approach for the treatment of human neoplasia?

    View details for DOI 10.1038/nrc1070

    View details for Web of Science ID 000183007900016

    View details for PubMedID 12724735

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