Cancer Institute A national cancer institute
designated cancer center

James D. Brooks

Publication Details

  • Even-skipped homeobox 1 is frequently hypermethylated in prostate cancer and predicts PSA recurrence.

    Truong M, Yang B, Wagner J, Kobayashi Y, Rajamanickam V, Brooks J, Jarrard DF. Br J Cancer. 2012; 107 (1): 100-7

    DNA methylation is an important epigenetic mechanism in prostate cancer (PCa) progression. Given the role of even-skipped homeobox 1 (EVX1) in the regulation of multiple genes during embryogenesis, we postulated that EVX1 methylation is altered in PCa progression.

    PubMedID: 22596233

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