Cancer Institute A national cancer institute
designated cancer center

Stefanie S. Jeffrey, MD

Publication Details

  • Ultrasound tissue characterization of breast biopsy specimens: Expanded study ULTRASONIC IMAGING MORTENSEN, C. L., Edmonds, P. D., Gorfu, Y., Hill, J. R., Jensen, J. F., Schattner, P., Shifrin, L. A., VALDES, A. D., Jeffrey, S. S., Esserman, L. J. 1996; 18 (3): 215-230


    Tissue classification by examining sets of ultrasound parameters is an elusive goal. We report analysis of measurements of ultrasound speed, attenuation and backscatter in the range 3 to 8 MHz in breast tissues at 37 C. Statistical discriminant analysis and neural net analysis were employed. Data were acquired from 24 biopsy and 7 mastectomy specimens. Best separation of the classes normal, benign, and malignant occurred in the 18 cases where two tissue classes were present in the same specimen and parameters were corrected for within-patient mean; then 85-90% of cases in test sets were correctly classified. Most errors comprised misclassified benign cases. The neural net was comparable to discriminant analysis and slightly superior in separating normal and malignant classes.

    View details for Web of Science ID A1996WA72700004

    View details for PubMedID 9123674

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