Cancer Institute A national cancer institute
designated cancer center

BrianĀ Feldman

Publication Details

  • The development of androgen-independent prostate cancer NATURE REVIEWS CANCER Feldman, B. J., Feldman, D. 2001; 1 (1): 34-45


    The normal prostate and early-stage prostate cancers depend on androgens for growth and survival, and androgen ablation therapy causes them to regress. Cancers that are not cured by surgery eventually become androgen independent, rendering anti-androgen therapy ineffective. But how does androgen independence arise? We predict that understanding the pathways that lead to the development of androgen-independent prostate cancer will pave the way to effective therapies for these, at present, untreatable cancers.

    View details for Web of Science ID 000180397000012

    View details for PubMedID 11900250

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