Cancer Institute A national cancer institute
designated cancer center

Philip W. Lavori

Publication Details

  • LONG-TERM OUTCOME OF EPISODES OF MAJOR DEPRESSION - CLINICAL AND PUBLIC-HEALTH SIGNIFICANCE JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION Keller, M. B., Klerman, G. L., Lavori, P. W., Coryell, W., Endicott, J., Taylor, J. 1984; 252 (6): 788-792

    Abstract:

    Twenty-one percent (20/97) of patients with an episode of major depressive disorder and no history of chronic minor depression who sought treatment at five university medical centers had not recovered after two years of prospective follow-up. The rate of recovery was highest in the three months after entry into the study, with a notable decrease in rate after one year. Most patients who did not recover had severe depressive symptoms throughout the two years of follow-up. Long duration of episode before entry into the study, inpatient hospitalization status at entry, intact marriage, low family income, admitting research center, and a history of nonaffective psychiatric disorders (including alcoholism) predicted a chronic course. The implications of these findings for clinicians, researchers, and public health planners are discussed.

    View details for Web of Science ID A1984TD16800020

    View details for PubMedID 6748178

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