Cancer Institute A national cancer institute
designated cancer center

Willard ("Bill") E. Fee, Jr.

Publication Details

  • SAFETY OF I-125 AND IR-192 IMPLANTS TO THE CANINE CAROTID-ARTERY - PRELIMINARY-REPORT LARYNGOSCOPE Fee, W. E., Goffinet, D. R., Fajardo, L. F., GUTHANER, D., HANDEN, C. 1985; 95 (3): 317-320

    Abstract:

    Thirty-nine healthy dogs underwent a simulated radical neck dissection followed by implantation of either 125Iodine (125I) or 192Iridium (192Ir) in various dose regimes randomized prospectively from 3,000 to 30,000 rad. Bilateral selective carotid angiography was performed immediately postoperatively and at six months and one year. No significant effects occurred to the animals who received 15,000 rad 125I or 6,000 rad 192Ir. In the higher dosed animals the 125I treated group fared better than the 192Ir treated group, probably due to the lower dose rate delivery. All surviving animals will be maintained an additional year to determine the late effects of brachytherapy irradiation to the carotid artery.

    View details for Web of Science ID A1985ADK4500015

    View details for PubMedID 3974384

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