Cancer Institute A national cancer institute
designated cancer center

Willard ("Bill") E. Fee, Jr.

Publication Details

  • SAFETY OF I-125 AND IR-192 IMPLANTS TO THE CANINE CAROTID-ARTERY - LONG-TERM RESULTS ACTA OTO-LARYNGOLOGICA Fee, W. E., Goffinet, D. R., Fajardo, L. F., GUTHANER, D., HANDEN, C. 1987; 103 (5-6): 514-518

    Abstract:

    Thirty-nine healthy dogs underwent a simulated radical neck dissection followed by implantation of either 125Iodine (125I) or 192Iridium (192Ir) in various dose regimes randomized prospectively from 3,000 to 30,000 rad. Bilateral selective carotid angiography was performed immediately postoperatively and at 6, 12, 18, and 24 months. No significant effects occurred to the animals who received 15,000 rad 125I or 6,000 rad 192Ir. In the higher dosed animals the 125I-treated group fared better than the 192Ir-treated group, probably due to the lower dose rate delivery. Fewer and less serious complications occurred in the 125I-treated group, but this group developed more complications after one year than the Iridium group.

    View details for Web of Science ID A1987H681100028

    View details for PubMedID 3618180

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