Cancer Institute A national cancer institute
designated cancer center

Philip W. Lavori

Publication Details

  • COURSE OF MAJOR DEPRESSION IN NON-REFERRED ADOLESCENTS - A RETROSPECTIVE STUDY JOURNAL OF AFFECTIVE DISORDERS Keller, M. B., Beardslee, W., Lavori, P. W., Wunder, J., DRS, D. L., SAMUELSON, H. 1988; 15 (3): 235-243

    Abstract:

    This article reports on a naturalistic study of the course of illness of 38 children diagnosed as having a current or past episode of major depression out of a sample of 275 children who were selected by a method not related to their psychopathology or treatment-seeking behavior. Assessments of the presence of depression and the course of this disorder were made using structured clinical interviews (DICA and DICA-P) and a criterion-based diagnostic system (DSM-III). Longitudinal methods of data analysis included the use of life tables. The proportion of children depressed for 2 years closely resembles the results found in investigations of children who sought treatment for a psychiatric disorder. The probability of remaining depressed in these children was 21% at 1 year after onset, and 10% at the 2-year point. This parallels the rate of chronicity and the decline in rates of recovery which occur over time in adult depression.

    View details for Web of Science ID A1988Q973300004

    View details for PubMedID 2975296

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