Cancer Institute A national cancer institute
designated cancer center

Philip W. Lavori

Publication Details

  • LACK OF STABILITY OF THE RDC ENDOGENOUS SUBTYPE IN CONSECUTIVE EPISODES OF MAJOR DEPRESSION JOURNAL OF AFFECTIVE DISORDERS Young, M. A., Keller, M. B., Lavori, P. W., Scheftner, W. A., Fawcett, J. A., Endicott, J., Hirschfeld, R. M. 1987; 12 (2): 139-143


    The stability of the endogenous subtype of major depressive disorder was examined within individuals across consecutive episodes. The subjects were 119 probands from the NIMH Collaborative Depression Study who experienced at least two episodes of unipolar major depressive disorder within a two-year period of biannual evaluations. Structured data collection methods and Research Diagnostic Criteria were employed. The inter-episode stability of subtype diagnosis was low, never producing a kappa of greater than 0.25. This result was not attributable to threshold for diagnosis, time between episodes, differences in severity, or changes in raters.

    View details for Web of Science ID A1987H664300006

    View details for PubMedID 2955005

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