Cancer Institute A national cancer institute
designated cancer center

Russ B. Altman

Publication Details

  • Translational Bioinformatics: Linking the Molecular World to the Clinical World CLINICAL PHARMACOLOGY & THERAPEUTICS Altman, R. B. 2012; 91 (6): 994-1000


    Translational bioinformatics represents the union of translational medicine and bioinformatics. Translational medicine moves basic biological discoveries from the research bench into the patient-care setting and uses clinical observations to inform basic biology. It focuses on patient care, including the creation of new diagnostics, prognostics, prevention strategies, and therapies based on biological discoveries. Bioinformatics involves algorithms to represent, store, and analyze basic biological data, including DNA sequence, RNA expression, and protein and small-molecule abundance within cells. Translational bioinformatics spans these two fields; it involves the development of algorithms to analyze basic molecular and cellular data with an explicit goal of affecting clinical care.

    View details for DOI 10.1038/clpt.2012.49

    View details for Web of Science ID 000304245800017

    View details for PubMedID 22549287

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