Cancer Institute A national cancer institute
designated cancer center

Atul Butte

Publication Details

  • Translational bioinformatics: linking knowledge across biological and clinical realms JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION Sarkar, I. N., Butte, A. J., Lussier, Y. A., Tarczy-Hornoch, P., Ohno-Machado, L. 2011; 18 (4): 354-357

    Abstract:

    Nearly a decade since the completion of the first draft of the human genome, the biomedical community is positioned to usher in a new era of scientific inquiry that links fundamental biological insights with clinical knowledge. Accordingly, holistic approaches are needed to develop and assess hypotheses that incorporate genotypic, phenotypic, and environmental knowledge. This perspective presents translational bioinformatics as a discipline that builds on the successes of bioinformatics and health informatics for the study of complex diseases. The early successes of translational bioinformatics are indicative of the potential to achieve the promise of the Human Genome Project for gaining deeper insights to the genetic underpinnings of disease and progress toward the development of a new generation of therapies.

    View details for DOI 10.1136/amiajnl-2011-000245

    View details for Web of Science ID 000292061700003

    View details for PubMedID 21561873

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