Ash A. Alizadeh, MD/PhD
Publications
- Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia. JAMA. 2010; (24): 2706-15
- Therapeutic Antibody Targeting of CD47 Synergizes with Rituximab to Completely Eradicate Human B-Cell Lymphoma Cell. 2010; (5): 699-713
- CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell. 2009; (2): 286-99
- Molecular outcome prediction in diffuse large-B-cell lymphoma. N Engl J Med. 2009; (26): 2794-5
- SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data. Nucleic Acids Res. 2003; (1): 219-23
- Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 2000; (6769): 503-11
- The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. Cold Spring Harb Symp Quant Biol. 1999: 71-8
- Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation. Nat Commun. 2013: 1338
- Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma. Blood. 2013; (9): 1604-11
- High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells. Blood. 2013; (8): 1367-76
- Identification of gene microarray expression profiles in patients with chronic graft-versus-host disease following allogeneic hematopoietic cell transplantation. Clin Immunol. 2013; (1): 124-135
- Rituximab use and survival after diffuse large B-cell or follicular lymphoma: a population-based study. Leuk Lymphoma. 2013; (4): 743-51
- Utility in prognostic value added by molecular profiles for diffuse large B-cell lymphoma. Blood. 2013; (15): 3052-4
- A retrospective study evaluating the efficacy and safety of bendamustine in the treatment of mantle cell lymphoma. Leuk Lymphoma. 2012; (7): 1299-305
- CD137 is expressed in follicular dendritic cell tumors and in classical Hodgkin and T-cell lymphomas: diagnostic and therapeutic implications. Am J Pathol. 2012; (3): 795-803
- Correction: Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. Arthritis Res Ther. 2012; (4): 403
- First isolation of Cryptococcus uzbekistanensis from an immunocompromised patient with Lymphoma. J Clin Microbiol. 2012; (3): 1125-7
- Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma. PLoS One. 2012; (10): e46117
- Self-antigen recognition by follicular lymphoma B-cell receptors. Blood. 2012; (20): 4182-90
- Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. Arthritis Res Ther. 2012; (1): R25
- The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proc Natl Acad Sci U S A. 2012; (17): 6662-7
- The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses. J Exp Med. 2012; (8): 1427-35
- Three differentiation states risk-stratify bladder cancer into distinct subtypes. Proc Natl Acad Sci U S A. 2012; (6): 2078-83
- Treatment advances have not improved the early death rate in acute promyelocytic leukemia. Haematologica. 2012; (1): 133-6
- A few good genes: simple, biologically motivated signatures for cancer prognosis. Cell Cycle. 2011; (21): 3615-6
- A proteomic approach for the identification of novel lysine methyltransferase substrates. Epigenetics Chromatin. 2011: 19
- CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies. Blood. 2011; (8): 2423-32
- Impact of TET2 mutations on mRNA expression and clinical outcomes in MDS patients treated with DNA methyltransferase inhibitors. Hematol Oncol. 2011; (3): 157-60
- Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment. Blood. 2011; (5): 1350-8
- Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker. Proc Natl Acad Sci U S A. 2011; (12): 5009-14
- Surprise! HSC are aberrant in chronic lymphocytic leukemia. Cancer Cell. 2011; (2): 135-6
- Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia. Cancer Res. 2011; (4): 1374-84
- Utility of positron emission tomography scans in mantle cell lymphoma. Am J Hematol. 2011; (10): 841-5
- B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Proc Natl Acad Sci U S A. 2010; (29): 12747-54
- Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47. Sci Transl Med. 2010; (63): 63ra94
- Expression profiles of adult T-cell leukemia-lymphoma and associations with clinical responses to zidovudine and interferon alpha. Leuk Lymphoma. 2010; (7): 1200-16
- Immunophenotypic features of acute myeloid leukemia with inv(3)(q21q26.2)/t(3;3)(q21;q26.2). Leuk Res. 2010; (5): 594-7
- Is Time of the Essence in Adult Acute Myeloid Leukemia (AML)? Time to Blast Clearance and Time to Induction Therapy Fail to Predict Overall Survival (OS) Blood (e-Letter). 2010; (1): 28-36
- Second-line mitoxantrone, etoposide, and cytarabine for acute myeloid leukemia: a single-center experience. Am J Hematol. 2010; (11): 877-81
- A pluripotency signature predicts histological transformation and influences survival in follicular lymphoma patients Blood. 2009
- Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion. Blood. 2009; (16): 3431-8
- Double trouble in follicular lymphoma: A rare and unusual synergy of oncogenes in the germinal center. Leuk Lymphoma. 2008; (3): 377-80
- Evaluation and management of angioimmunoblastic T-cell lymphoma: a review of current approaches and future strategies. Clin Adv Hematol Oncol. 2008; (12): 899-909
- Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray. J Clin Microbiol. 2007; (7): 2340-3
- Cell-type specific gene expression profiles of leukocytes in human peripheral blood. BMC Genomics. 2006: 115
- Distinct IL-4-induced gene expression, proliferation, and intracellular signaling in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas. Blood. 2005; (7): 2924-32
- AID is expressed in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas and is not correlated with intraclonal heterogeneity. Leukemia. 2004; (11): 1775-9
- Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response. Blood. 2004; (5): 1428-34
- Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol. 2004; (2): E7
- Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes. N Engl J Med. 2004; (18): 1828-37
- Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock. Lancet. 2004; (9404): 203-9
- HGAL is a novel interleukin-4-inducible gene that strongly predicts survival in diffuse large B-cell lymphoma. Blood. 2003; (2): 433-40
- Individuality and variation in gene expression patterns in human blood. Proc Natl Acad Sci U S A. 2003; (4): 1896-901
- Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling N Engl J Med. 2003; (2): 125-38
- Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues. Arthritis Rheum. 2003; (8): 2132-45
- T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. PLoS Biol. 2003; (2): E53
- Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations. Blood. 2003; (8): 3109-17
- Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proc Natl Acad Sci U S A. 2002; (18): 11796-801
- In vivo regulation of human skeletal muscle gene expression by thyroid hormone. Genome Res. 2002; (2): 281-91
- Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays. Am J Pathol. 2002; (5): 1557-65
- Stereotyped and specific gene expression programs in human innate immune responses to bacteria. Proc Natl Acad Sci U S A. 2002; (2): 972-7
- The t(14;18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile. Blood. 2002; (7): 2285-90
- Transformation of follicular lymphoma to diffuse large-cell lymphoma: alternative patterns with increased or decreased expression of c-myc and its regulated genes. Proc Natl Acad Sci U S A. 2002; (13): 8886-91
- Genomic analysis of renal allograft dysfunction using cDNA microarrays. Transplant Proc. 2001 Feb-Mar; (1-2): 297-8
- Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med. 2001; (11): 1639-47
- Towards a novel classification of human malignancies based on gene expression patterns. J Pathol. 2001; (1): 41-52
- 'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns. Genome Biol. 2000; (2): RESEARCH0003
- Examining the living genome in health and disease with DNA microarrays. JAMA. 2000; (17): 2298-9
- Genomic-scale gene expression profiling of normal and malignant immune cells. Curr Opin Immunol. 2000; (2): 219-25
- Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas. Proc Natl Acad Sci U S A. 2000; (18): 10209-13
- Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nat Genet. 1999; (1): 41-6
- Probing lymphocyte biology by genomic-scale gene expression analysis. J Clin Immunol. 1998; (6): 373-9
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