Renee A. Reijo Pera, Ph.D.
Publications
- Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage. Nat Commun. 2012: 1251
- LRRK2 mutant iPSC-Derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell. 2011: 114
- NANOS3 function in human germ cell development. Human Molecular Genetics (in press).. 2011
- Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells. Hum Mol Genet. 2010: 752-62
- Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Nat Biotechnol. 2010; (10): 1115-21
- Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation. Nature. 2009; (7270): 222-5
- The road to pluripotence: the research response to the embryonic stem cell debate. Hum Mol Genet. 2008; (R1): R3-9
- Human induced pluripotent stem cell-derived endothelial cells exhibit functional heterogeneity. Am J Transl Res. 2013; (1): 21-35
- Reprogramming of fibroblasts from older women with pelvic floor disorders alters cellular behavior associated with donor age. Stem Cells Transl Med. 2013; (2): 118-28
- Divergent RNA-binding proteins, DAZL and VASA, induce meiotic progression in human germ cells derived in vitro. Stem Cells. 2012; (3): 441-51
- Genetic markers of ovarian follicle number and menopause in women of multiple ethnicities. Hum Genet. 2012; (11): 1709-24
- Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women. Hum Reprod. 2012; (2): 594-608
- Human amniotic mesenchymal stem cell-derived induced pluripotent stem cells may generate a universal source of cardiac cells. Stem Cells Dev. 2012; (15): 2798-808
- Modeling Parkinson's disease using induced pluripotent stem cells. Curr Neurol Neurosci Rep. 2012; (3): 237-42
- Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells. Proc Natl Acad Sci U S A. 2012; (1): 215-20
- Theranostic effect of serial manganese-enhanced magnetic resonance imaging of human embryonic stem cell derived teratoma. Magn Reson Med. 2012; (2): 595-9
- Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arterioscler Thromb Vasc Biol. 2011; (11): e72-9
- In vivo molecular MRI of cell survival and teratoma formation following embryonic stem cell transplantation into the injured murine myocardium. Magn Reson Med. 2011; (5): 1374-81
- NANOS3 function in human germ cell development. Hum Mol Genet. 2011; (11): 2238-50
- Non-invasive imaging of human embryos to predict developmental competence. Placenta. 2011: S264-7
- Pumilio-2 function in the mouse nervous system. PLoS One. 2011; (10): e25932
- Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature. 2011; (7351): 399-402
- Human primordial germ cell formation is diminished by exposure to environmental toxicants acting through the AHR signaling pathway. Toxicol Sci. 2010; (1): 218-24
- Parthenogenic blastocysts derived from cumulus-free in vitro matured human oocytes. PLoS One. 2010; (6): e10979
- Testicular germline stem cells. Nat Rev Urol. 2010; (2): 94-100
- Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro. PLoS One. 2009; (5): e5654
- Enhanced generation of induced pluripotent stem cells from a subpopulation of human fibroblasts. PLoS One. 2009; (9): e7118
- Gene expression profiles of human inner cell mass cells and embryonic stem cells. Differentiation. 2009; (1): 18-23
- Instructing an embryonic stem cell-derived oocyte fate: lessons from endogenous oogenesis. Endocr Rev. 2009; (3): 264-83
- Transplantation directs oocyte maturation from embryonic stem cells and provides a therapeutic strategy for female infertility. Hum Mol Genet. 2009; (22): 4376-89
- Culturing human embryonic stem cells in feeder-free conditions. CSH Protoc. 2008: pdb.prot5044
- Culturing human embryonic stem cells with mouse embryonic fibroblast feeder cells. CSH Protoc. 2008: pdb.prot5042
- Defining human embryo phenotypes by cohort-specific prognostic factors. PLoS One. 2008; (7): e2562
- High-efficiency stem cell fusion-mediated assay reveals Sall4 as an enhancer of reprogramming PLoSOne. 2008; (4): e1955
- Human germ cell lineage differentiation from embryonic stem cells. CSH Protoc. 2008: pdb.prot5048
- Metaphase spreads and spectral karyotyping of human embryonic stem cells. CSH Protoc. 2008: pdb.prot5047
- Method for single-cell sorting and expansion of genetically modified human embryonic stem cells. CSH Protoc. 2008: pdb.prot5045
- Noninvasive human nuclear transfer with embryonic stem cells. CSH Protoc. 2008: pdb.prot5040
- Preparation of human foreskin fibroblasts for human embryonic stem cell culture. CSH Protoc. 2008: pdb.prot5043
- Preparation of mouse embryonic fibroblast feeder cells for human embryonic stem cell culture. CSH Protoc. 2008: pdb.prot5041
- A method for single-cell sorting and expansion of genetically modified human embryonic stem cells. Stem Cells Dev. 2007; (1): 109-17
- Intermolecular interactions of homologs of germ plasm components in mammalian germ cells. Dev Biol. 2007; (2): 417-31
- A gene trap knockout of the abundant sperm tail protein, outer dense fiber 2, results in preimplantation lethality. Genesis. 2006; (11): 515-22
- Bone morphogenetic proteins induce germ cell differentiation from human embryonic stem cells. Stem Cells Dev. 2006; (6): 831-7
- Evolutionary comparison of the reproductive genes, DAZL and BOULE, in primates with and without DAZ. Dev Genes Evol. 2006; (3): 158-68
- Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene. Cancer Res. 2006; (1): 290-302
- Modeling human germ cell development with embryonic stem cells. Regen Med. 2006; (1): 85-93
- Novel missense mutations of the Deleted-in-AZoospermia-Like (DAZL) gene in infertile women and men. Reprod Biol Endocrinol. 2006: 40
- A new era in the ethics of human embryonic stem cell research. Stem Cells. 2005 Nov-Dec; (10): 1454-9
- Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma. Cancer. 2005; (10): 2255-65
- Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind. Genomics. 2005; (1): 92-105
- Interaction of the conserved meiotic regulators, BOULE (BOL) and PUMILIO-2 (PUM2). Mol Reprod Dev. 2005; (3): 290-8
- Recombination in men with Klinefelter syndrome. Reproduction. 2005; (2): 223-9
- Association of meiotic arrest with lack of BOULE protein expression in infertile men. J Clin Endocrinol Metab. 2004; (4): 1926-33
- Defective recombination in infertile men. Hum Mol Genet. 2004; (22): 2875-83
- Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma. Stem Cells. 2004; (2): 169-79
- Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells. Genomics. 2004; (5): 834-43
- Spontaneous differentiation of germ cells from human embryonic stem cells in vitro. Hum Mol Genet. 2004; (7): 727-39
- The unique transcriptome through day 3 of human preimplantation development. Hum Mol Genet. 2004; (14): 1461-70
- Unique gene expression signatures of independently-derived human embryonic stem cell lines. Hum Mol Genet. 2004; (6): 601-8
- Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells. Dev Genes Evol. 2003; (3): 120-6
- Feasibility of global gene expression analysis in testicular biopsies from infertile men. Mol Reprod Dev. 2003; (4): 403-21
- Human BOULE gene rescues meiotic defects in infertile flies. Hum Mol Genet. 2003; (2): 169-75
- Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins. Proc Natl Acad Sci U S A. 2003; (2): 538-43
- Current and future genetic screening for male infertility. Urol Clin North Am. 2002; (4): 767-92
- Generation and in vitro differentiation of a spermatogonial cell line. Science. 2002; (5580): 392-5
- A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans. Proc Natl Acad Sci U S A. 2001; (13): 7414-9
- Impaired spermatogenesis in men with congenital absence of the vas deferens. Hum Reprod. 2001; (3): 529-33
- Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair. Mol Cell Endocrinol. 2001; (1-2): 41-9
- Response to varicocelectomy in oligospermic men with and without defined genetic infertility. Urology. 2001; (3): 530-5
- DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice. Biol Reprod. 2000; (5): 1490-6
- Increased frequency of mutations in DNA from infertile men with meiotic arrest. Hum Reprod. 2000; (6): 1289-94
- Male sperm motility dictated by mother's mtDNA. Am J Hum Genet. 2000; (3): 543-8
- Human DAZL1 encodes a candidate fertility factor in women that localizes to the prenatal and postnatal germ cells. Hum Reprod. 1999; (10): 2531-6
- Azoospermic men with deletion of the DAZ gene cluster are capable of completing spermatogenesis: fertilization, normal embryonic development and pregnancy occur when retrieved testicular spermatozoa are used for intracytoplasmic sperm injection. Hum Reprod. 1997; (3): 503-8
- Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty. Genomics. 1996; (2): 346-52
- Severe oligozoospermia resulting from deletions of azoospermia factor gene on Y chromosome. Lancet. 1996; (9011): 1290-3
- The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned. Nat Genet. 1996; (3): 292-9
- Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nat Genet. 1995; (4): 383-93
- Gonadoblastoma: molecular definition of the susceptibility region on the Y chromosome. Am J Hum Genet. 1995; (6): 1400-7
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