Mei-Chiung Shih

Publications

• Adaptive trial designs. Lai TL, Lavori PW, Shih MC. Annu Rev Pharmacol Toxicol. 2012: 52 101-10
• Clinical trial designs for testing biomarker-based personalized therapies. Lai TL, Lavori PW, Shih MC, Sikic BI. Clin Trials. 2012; 9 (2): 141-54
• Sequential design of phase II-III cancer trials. Lai TL, Lavori PW, Shih MC. Stat Med. 2012; 31 (18): 1944-60
• A biosensor platform for rapid antimicrobial susceptibility testing directly from clinical samples. Mach KE, Mohan R, Baron EJ, Shih MC, Gau V, Wong PK, Liao JC. J Urol. 2011; 185 (1): 148-53
• An evaluation of patient self-testing competency of prothrombin time for managing anticoagulation: pre-randomization results of VA Cooperative Study #481--The Home INR Study (THINRS). Dolor RJ, Ruybalid RL, Uyeda L, Edson RG, Phibbs C, Vertrees JE, Shih MC, Jacobson AK, Matchar DB. J Thromb Thrombolysis. 2010; 30 (3): 263-75
• Defining acute lung disease in children with the oxygenation saturation index. Thomas NJ, Shaffer ML, Willson DF, Shih MC, Curley MA. Pediatr Crit Care Med. 2010; 11 (1): 12-7
• Effect of home testing of international normalized ratio on clinical events. Matchar DB, Jacobson A, Dolor R, Edson R, Uyeda L, Phibbs CS, Vertrees JE, Shih MC, Holodniy M, Lavori P. N Engl J Med. 2010; 363 (17): 1608-20
• Effects of the thyromimetic agent diiodothyropropionic acid on body weight, body mass index, and serum lipoproteins: a pilot prospective, randomized, controlled study. Ladenson PW, McCarren M, Morkin E, Edson RG, Shih MC, Warren SR, Barnhill JG, Churby L, Thai H, O'Brien T, Anand I, Warner A, Hattler B, Dunlap M, Erikson J, Goldman S. J Clin Endocrinol Metab. 2010; 95 (3): 1349-54
• Electrochemical immunosensor detection of urinary lactoferrin in clinical samples for urinary tract infection diagnosis. Pan Y, Sonn GA, Sin ML, Mach KE, Shih MC, Gau V, Wong PK, Liao JC. Biosens Bioelectron. 2010; 26 (2): 649-54
• Sequential generalized likelihood ratio tests for vaccine safety evaluation. Shih MC, Lai TL, Heyse JF, Chen J. Stat Med. 2010; 29 (26): 2698-708
• Effect of the MTHFR C677T and A1298C polymorphisms on survival in patients with advanced CKD and ESRD: a prospective study. Jamison RL, Shih MC, Humphries DE, Guarino PD, Kaufman JS, Goldfarb DS, Warren SR, Gaziano JM, Lavori P. Am J Kidney Dis. 2009; 53 (5): 779-89
• Multiplex pathogen identification for polymicrobial urinary tract infections using biosensor technology: a prospective clinical study. Mach KE, Du CB, Phull H, Haake DA, Shih MC, Baron EJ, Liao JC. J Urol. 2009; 182 (6): 2735-41
• A new approach to modeling covariate effects and individualization in population pharmacokinetics-pharmacodynamics. Lai TL, Shih MC, Wong SP. J Pharmacokinet Pharmacodyn. 2006; 33 (1): 49-74
• Flexible modeling via a hybrid estimation scheme in generalized mixed models for longitudinal data. Leung Lai T, Shih MC, Wong SP. Biometrics. 2006; 62 (1): 159-67
• Modified Haybittle-Peto group sequential designs for testing superiority and non-inferiority hypotheses in clinical trials. Lai TL, Shih MC, Zhu G. Stat Med. 2006; 25 (7): 1149-67
• Tests for genetic association using family data. Shih MC, Whittemore AS. Genet Epidemiol. 2002; 22 (2): 128-45
• Allele-sharing among affected relatives: non-parametric methods for identifying genes. Shih MC, Whittemore AS. Stat Methods Med Res. 2001; 10 (1): 27-55