Alejandro Sweet-Cordero

Publications

• Mathematical Modeling of Tumor Cell Proliferation Kinetics and Label Retention in a Mouse Model of Lung Cancer. Zheng Y, Moore H, Piryatinska A, Solis T, Sweet-Cordero EA. Cancer Res. 2013
• Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for CLCF1 and IL-6 in non-small cell lung cancer in vivo. Vicent S, Sayles LC, Vaka D, Khatri P, Gevaert O, Chen R, Zheng Y, Gillespie AK, Clarke N, Xu Y, Shrager J, Hoang CD, Plevritis S, Butte AJ, Sweet-Cordero EA. Cancer Res. 2012; 72 (22): 5744-56
• Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Oliver TG, Mercer KL, Sayles LC, Burke JR, Mendus D, Lovejoy KS, Cheng MH, Subramanian A, Mu D, Powers S, Crowley D, Bronson RT, Whittaker CA, Bhutkar A, Lippard SJ, Golub T, Thomale J, Jacks T, Sweet-Cordero EA. Genes Dev. 2010; 24 (8): 837-52
• Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models. Vicent S, Chen R, Sayles LC, Lin C, Walker RG, Gillespie AK, Subramanian A, Hinkle G, Yang X, Saif S, Root DE, Huff V, Hahn WC, Sweet-Cordero EA. J Clin Invest. 2010; 120 (11): 3940-52
• The phosphatase PP2A links glutamine to the tumor suppressor p53. Gwinn D, Sweet-Cordero EA. Mol Cell. 2013; 50 (2): 157-8
• Two Is Better Than One: Combining IGF1R and MEK Blockade as a Promising Novel Treatment Strategy Against KRAS-Mutant Lung Cancer. Chen R, Sweet-Cordero EA. Cancer Discov. 2013; 3 (5): 491-3
• Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A, Sage J, Butte AJ. Sci Transl Med. 2011; 3 (96): 96ra77
• Expression and silencing of the microtubule-associated protein Tau in breast cancer cells. Spicakova T, O'Brien MM, Duran GE, Sweet-Cordero A, Sikic BI. Mol Cancer Ther. 2010; 9 (11): 2970-81
• Hypoxia in models of lung cancer: implications for targeted therapeutics. Graves EE, Vilalta M, Cecic IK, Erler JT, Tran PT, Felsher D, Sayles L, Sweet-Cordero A, Le QT, Giaccia AJ. Clin Cancer Res. 2010; 16 (19): 4843-52
• Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Schaffer BE, Park KS, Yiu G, Conklin JF, Lin C, Burkhart DL, Karnezis AN, Sweet-Cordero EA, Sage J. Cancer Res. 2010; 70 (10): 3877-83
• Requirement for Rac1 in a K-ras induced lung cancer in the mouse. Kissil JL, Walmsley MJ, Hanlon L, Haigis KM, Bender Kim CF, Sweet-Cordero A, Eckman MS, Tuveson DA, Capobianco AJ, Tybulewicz VL, Jacks T. Cancer Res. 2007; 67 (17): 8089-94
• Comparison of gene expression and DNA copy number changes in a murine model of lung cancer. Sweet-Cordero A, Tseng GC, You H, Douglass M, Huey B, Albertson D, Jacks T. Genes Chromosomes Cancer. 2006; 45 (4): 338-48
• An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis. Sweet-Cordero A, Mukherjee S, Subramanian A, You H, Roix JJ, Ladd-Acosta C, Mesirov J, Golub TR, Jacks T. Nat Genet. 2005; 37 (1): 48-55
• MicroRNA expression profiles classify human cancers. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR. Nature. 2005; 435 (7043): 834-8