Billy W. Loo, Jr., MD, PhD, DABR

Publications

• Metabolic tumor volume predicts disease progression and survival in patients with squamous cell carcinoma of the anal canal. Bazan JG, Koong AC, Kapp DS, Quon A, Graves EE, Loo BW, Chang DT. J Nucl Med. 2013; 54 (1): 27-32
• Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy. Hong JC, Eclov NC, Yu Y, Rao AK, Dieterich S, Le QT, Diehn M, Sze DY, Loo BW, Kothary N, Maxim PG. J Appl Clin Med Phys. 2013; 14 (2): 4046
• Non-Small Cell Lung Cancer, Version 2.2013. Ettinger DS, Akerley W, Borghaei H, Chang AC, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Govindan R, Grannis FW, Grant SC, Horn L, Jahan TM, Komaki R, Kong FM, Kris MG, Krug LM, Lackner RP, Lennes IT, Loo BW, Martins R, Otterson GA, Patel JD, Pinder-Schenck MC, Pisters KM, Reckamp K, Riely GJ, Rohren E, Shapiro TA, Swanson SJ, Tauer K, Wood DE, Yang SC, Gregory K, Hughes M. J Natl Compr Canc Netw. 2013; 11 (6): 645-653
• Radiotherapy for nonadenoid cystic carcinomas of major salivary glands. Chung MP, Tang C, Chan C, Hara WY, Loo BW, Kaplan MJ, Fischbein N, Le QT, Chang DT. Am J Otolaryngol. 2013
• Small cell lung cancer. Kalemkerian GP, Akerley W, Bogner P, Borghaei H, Chow LQ, Downey RJ, Gandhi L, Ganti AK, Govindan R, Grecula JC, Hayman J, Heist RS, Horn L, Jahan T, Koczywas M, Loo BW, Merritt RE, Moran CA, Niell HB, O'Malley J, Patel JD, Ready N, Rudin CM, Williams CC, Gregory K, Hughes M. J Natl Compr Canc Netw. 2013; 11 (1): 78-98
• The optimal use of radiotherapy in small cell lung cancer. Shultz DB, Grecula JC, Hayman J, Diehn M, Loo BW. J Natl Compr Canc Netw. 2013; 11 (1): 107-14
• Thymomas and thymic carcinomas. Ettinger DS, Riely GJ, Akerley W, Borghaei H, Chang AC, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Govindan R, Grannis FW, Grant SC, Horn L, Jahan TM, Komaki R, Kong FM, Kris MG, Krug LM, Lackner RP, Lennes IT, Loo BW, Martins R, Otterson GA, Patel JD, Pinder-Schenck MC, Pisters KM, Reckamp K, Rohren E, Shapiro TA, Swanson SJ, Tauer K, Wood DE, Yang SC, Gregory K, Hughes M. J Natl Compr Canc Netw. 2013; 11 (5): 562-76
• Esophageal tolerance to high-dose stereotactic ablative radiotherapy. Abelson JA, Murphy JD, Loo BW, Chang DT, Daly ME, Wiegner EA, Hancock S, Chang SD, Le QT, Soltys SG, Gibbs IC. Dis Esophagus. 2012 Sep-Oct; 25 (7): 623-9
• American College of Chest Physicians and Society of Thoracic Surgeons consensus statement for evaluation and management for high-risk patients with stage I non-small cell lung cancer. Donington J, Ferguson M, Mazzone P, Handy J, Schuchert M, Fernando H, Loo B, Lanuti M, de Hoyos A, Detterbeck F, Pennathur A, Howington J, Landreneau R, Silvestri G. Chest. 2012; 142 (6): 1620-35
• An automated method for comparing motion artifacts in cine four-dimensional computed tomography images. Cui G, Jew B, Hong JC, Johnston EW, Loo BW, Maxim PG. J Appl Clin Med Phys. 2012; 13 (6): 3838
• Interim-treatment quantitative PET parameters predict progression and death among patients with Hodgkin's disease. Tseng D, Rachakonda LP, Su Z, Advani R, Horning S, Hoppe RT, Quon A, Graves EE, Loo BW, Tran PT. Radiat Oncol. 2012: 7 5
• Intrafraction verification of gated RapidArc by using beam-level kilovoltage X-ray images. Li R, Mok E, Chang DT, Daly M, Loo BW, Diehn M, Le QT, Koong A, Xing L. Int J Radiat Oncol Biol Phys. 2012; 83 (5): e709-15
• Malignant pleural mesothelioma. Ettinger DS, Akerley W, Borghaei H, Chang A, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Ganti AK, Govindan R, Grannis FW, Horn L, Jahan TM, Jahanzeb M, Kessinger A, Komaki R, Kong FM, Kris MG, Krug LM, Lennes IT, Loo BW, Martins R, O'Malley J, Osarogiagbon RU, Otterson GA, Patel JD, Schenck MP, Pisters KM, Reckamp K, Riely GJ, Rohren E, Swanson SJ, Wood DE, Yang SC. J Natl Compr Canc Netw. 2012; 10 (1): 26-41
• Metabolic imaging metrics correlate with survival in early stage lung cancer treated with stereotactic ablative radiotherapy. Abelson JA, Murphy JD, Trakul N, Bazan JG, Maxim PG, Graves EE, Quon A, Le QT, Diehn M, Loo BW. Lung Cancer. 2012; 78 (3): 219-24
• Metabolic tumor volume is an independent prognostic factor in patients treated definitively for non-small-cell lung cancer. Lee P, Bazan JG, Lavori PW, Weerasuriya DK, Quon A, Le QT, Wakelee HA, Graves EE, Loo BW. Clin Lung Cancer. 2012; 13 (1): 52-8
• Non-small cell lung cancer. Ettinger DS, Akerley W, Borghaei H, Chang AC, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Ganti AK, Govindan R, Grannis FW, Horn L, Jahan TM, Jahanzeb M, Kessinger A, Komaki R, Kong FM, Kris MG, Krug LM, Lennes IT, Loo BW, Martins R, O'Malley J, Osarogiagbon RU, Otterson GA, Patel JD, Pinder-Schenck MC, Pisters KM, Reckamp K, Riely GJ, Rohren E, Swanson SJ, Wood DE, Yang SC, Hughes M, Gregory KM. J Natl Compr Canc Netw. 2012; 10 (10): 1236-71
• Postchemoradiotherapy positron emission tomography predicts pathologic response and survival in patients with esophageal cancer. Jayachandran P, Pai RK, Quon A, Graves E, Krakow TE, La T, Loo BW, Koong AC, Chang DT. Int J Radiat Oncol Biol Phys. 2012; 84 (2): 471-7
• Prognostic value of metabolic tumor volume and velocity in predicting head-and-neck cancer outcomes. Chu KP, Murphy JD, La TH, Krakow TE, Iagaru A, Graves EE, Hsu A, Maxim PG, Loo B, Chang DT, Le QT. Int J Radiat Oncol Biol Phys. 2012; 83 (5): 1521-7
• Reproducibility of four-dimensional computed tomography-based lung ventilation imaging. Yamamoto T, Kabus S, von Berg J, Lorenz C, Chung MP, Hong JC, Loo BW, Keall PJ. Acad Radiol. 2012; 19 (12): 1554-65
• SU-D-BRB-01: 4D-CT Lung Ventilation Images Vary with 4D-CT Sorting Techniques. Yamamoto T, Kabus S, Lorenz C, Johnston E, Maxim P, Loo B, Keall P. Med Phys. 2012; 39 (6): 3614
• SU-E-J-177: Characterization of the Effect of ''Lung Detail'' CT Reconstruction Algorithm on Radiation Therapy Dose Calculation. Eclov N, Loo B, Graves E, Maxim P. Med Phys. 2012; 39 (6): 3693
• Stereotactic ablative radiotherapy for reirradiation of locally recurrent lung tumors. Trakul N, Harris JP, Le QT, Hara WY, Maxim PG, Loo BW, Diehn M. J Thorac Oncol. 2012; 7 (9): 1462-5
• TU-A-BRA-05: Lung Cancer Patient Feasibility Study for Emission Guided Radiation Therapy. Mazin S, Nanduri A, Yang J, Yamamoto T, Loo B, Graves E. Med Phys. 2012; 39 (6): 3888-9
• The management of patients with stage IIIA non-small cell lung cancer with N2 mediastinal node involvement. Martins RG, D'Amico TA, Loo BW, Pinder-Schenck M, Borghaei H, Chaft JE, Ganti AK, Kong FM, Kris MG, Lennes IT, Wood DE. J Natl Compr Canc Netw. 2012; 10 (5): 599-613
• Tumor volume-adapted dosing in stereotactic ablative radiotherapy of lung tumors. Trakul N, Chang CN, Harris J, Chapman C, Rao A, Shen J, Quinlan-Davidson S, Filion EJ, Wakelee HA, Colevas AD, Whyte RI, Dieterich S, Maxim PG, Hristov D, Tran P, Le QT, Loo BW, Diehn M. Int J Radiat Oncol Biol Phys. 2012; 84 (1): 231-7
• Validation that metabolic tumor volume predicts outcome in head-and-neck cancer. Tang C, Murphy JD, Khong B, La TH, Kong C, Fischbein NJ, Colevas AD, Iagaru AH, Graves EE, Loo BW, Le QT. Int J Radiat Oncol Biol Phys. 2012; 83 (5): 1514-20
• WE-C-BRB-05: Monte Carlo Simulations and Experimental Validation of Rapid Dose Delivery with Very High-Energy Electron Beams. Bazalova M, Maxim P, Tantawi S, Colby E, Koong A, Loo B. Med Phys. 2012; 39 (6): 3944
• Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity. Murphy JD, Chisholm KM, Daly ME, Wiegner EA, Truong D, Iagaru A, Maxim PG, Loo BW, Graves EE, Kaplan MJ, Kong C, Le QT. Radiother Oncol. 2011; 101 (3): 356-61
• Four-dimensional computed tomography pulmonary ventilation images vary with deformable image registration algorithms and metrics. Yamamoto T, Kabus S, Klinder T, von Berg J, Lorenz C, Loo BW, Keall PJ. Med Phys. 2011; 38 (3): 1348-58
• High retention and safety of percutaneously implanted endovascular embolization coils as fiducial markers for image-guided stereotactic ablative radiotherapy of pulmonary tumors. Hong JC, Yu Y, Rao AK, Dieterich S, Maxim PG, Le QT, Diehn M, Sze DY, Kothary N, Loo BW. Int J Radiat Oncol Biol Phys. 2011; 81 (1): 85-90
• Hypofractionation results in reduced tumor cell kill compared to conventional fractionation for tumors with regions of hypoxia. Carlson DJ, Keall PJ, Loo BW, Chen ZJ, Brown JM. Int J Radiat Oncol Biol Phys. 2011; 79 (4): 1188-95
• In Reply to Song et al. Brown M, Loo BW, Diehn M, Carlson DJ. Int J Radiat Oncol Biol Phys. 2011; 81 (4): 1194
• In reply to drs. Koch and evans. Brown JM, Loo BW, Diehn M, Carlson DJ. Int J Radiat Oncol Biol Phys. 2011; 80 (5): 1605
• Influence of Tumor Hypoxia on Stereotactic Ablative Radiotherapy (SABR): Response to Drs. Meyer and Timmerman. Brown M, Loo B, Diehn M, Carlson D. Int J Radiat Oncol Biol Phys. 2011; 79 (5): 1600
• Intensity-modulated radiotherapy for locally advanced cancers of the larynx and hypopharynx. Daly ME, Le QT, Jain AK, Maxim PG, Hsu A, Loo BW, Kaplan MJ, Fischbein NJ, Colevas AD, Pinto H, Chang DT. Head Neck. 2011; 33 (1): 103-11
• Intensity-modulated radiotherapy for oral cavity squamous cell carcinoma: patterns of failure and predictors of local control. Daly ME, Le QT, Kozak MM, Maxim PG, Murphy JD, Hsu A, Loo BW, Kaplan MJ, Fischbein NJ, Chang DT. Int J Radiat Oncol Biol Phys. 2011; 80 (5): 1412-22
• Investigation of four-dimensional computed tomography-based pulmonary ventilation imaging in patients with emphysematous lung regions. Yamamoto T, Kabus S, Klinder T, Lorenz C, von Berg J, Blaffert T, Loo BW, Keall PJ. Phys Med Biol. 2011; 56 (7): 2279-98
• Molecular imaging with 11C-PD153035 PET/CT predicts survival in non-small cell lung cancer treated with EGFR-TKI: a pilot study. Meng X, Loo BW, Ma L, Murphy JD, Sun X, Yu J. J Nucl Med. 2011; 52 (10): 1573-9
• Motion management and image guidance for thoracic tumor radiotherapy: clinical treatment programs. Loo BW, Kavanagh BD, Meyer JL. Front Radiat Ther Oncol. 2011: 43 271-91
• On-board imaging validation of optically guided stereotactic radiosurgery positioning system for conventionally fractionated radiotherapy for paranasal sinus and skull base cancer. Maxim PG, Loo BW, Murphy JD, Chu KP, Hsu A, Le QT. Int J Radiat Oncol Biol Phys. 2011; 81 (4): 1153-9
• Postradiation metabolic tumor volume predicts outcome in head-and-neck cancer. Murphy JD, La TH, Chu K, Quon A, Fischbein NJ, Maxim PG, Graves EE, Loo BW, Le QT. Int J Radiat Oncol Biol Phys. 2011; 80 (2): 514-21
• Reducing 4D CT artifacts using optimized sorting based on anatomic similarity. Johnston E, Diehn M, Murphy JD, Loo BW, Maxim PG. Med Phys. 2011; 38 (5): 2424-9
• Results from a single institution phase II trial of concurrent docetaxel/carboplatin/radiotherapy followed by surgical resection and consolidation docetaxel/carboplatin in stage III non-small-cell lung cancer. Das M, Donington JS, Murphy J, Kozak M, Eclov N, Whyte RI, Hoang CD, Zhou L, Le QT, Loo BW, Wakelee H. Clin Lung Cancer. 2011; 12 (5): 280-5
• Stereotactic ablative radiotherapy (SABR) for lung cancer: What does the future hold? Loo BW, J Thorac Dis. 2011; 3 (3): 150-2
• Stereotactic ablative radiotherapy: what's in a name? BW Loo Jr, JY Chang, LA Dawson, BD Kavanagh, AC Koong, S Senan, RD Timmerman. Practical Radiation Oncology. 2011; 1 (1): 38-39
• Tumor volume as a potential imaging-based risk-stratification factor in trimodality therapy for locally advanced non-small cell lung cancer. Kozak MM, Murphy JD, Schipper ML, Donington JS, Zhou L, Whyte RI, Shrager JB, Hoang CD, Bazan J, Maxim PG, Graves EE, Diehn M, Hara WY, Quon A, Le QT, Wakelee HA, Loo BW. J Thorac Oncol. 2011; 6 (5): 920-6
• What the diagnostic radiologist needs to know about radiation oncology. Terezakis SA, Heron DE, Lavigne RF, Diehn M, Loo BW. Radiology. 2011; 261 (1): 30-44
• Alternatives to surgery for early stage non-small cell lung cancer-ready for prime time? Das M, Abdelmaksoud MH, Loo BW, Kothary N. Curr Treat Options Oncol. 2010; 11 (1-2): 24-35
• CyberKnife stereotactic ablative radiotherapy for lung tumors. Gibbs IC, Loo BW. Technol Cancer Res Treat. 2010; 9 (6): 589-96
• Intensity-modulated radiotherapy in the treatment of oropharyngeal cancer: clinical outcomes and patterns of failure. Daly ME, Le QT, Maxim PG, Loo BW, Kaplan MJ, Fischbein NJ, Pinto H, Chang DT. Int J Radiat Oncol Biol Phys. 2010; 76 (5): 1339-46
• Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizer. Brown JM, Diehn M, Loo BW. Int J Radiat Oncol Biol Phys. 2010; 78 (2): 323-7
• Stereotactic body radiation therapy (stereotactic ablative radiotherapy) for stage I non-small cell lung cancer--updates of radiobiology, techniques, and clinical outcomes. Hadziahmetovic M, Loo BW, Timmerman RD, Mayr NA, Wang JZ, Huang Z, Grecula JC, Lo SS. Discov Med. 2010; 9 (48): 411-7
• Cooperative group research efforts in thoracic malignancies 2009: a review from the 10th Annual International Lung Cancer Congress. Wakelee H, Loo BW, Kernstine KH, Putnam JB, Edelman MJ, Vokes EE, Schiller JH, Baas P, Saijo N, Adjei A, Goss G, Choy H, Gandara DR. Clin Lung Cancer. 2009; 10 (6): 395-404
• Marked tumor response and fatal hemoptysis during radiation for lung cancer in a human immunodeficiency virus-positive patient taking nelfinavir. Chapman CH, Shen J, Filion EJ, Tran PT, Hara W, Asuncion A, Marko D, Wakelee H, Berry GJ, Dimmick KW, Loo BW, Green J. J Thorac Oncol. 2009; 4 (12): 1587-9
• Metabolic tumor volume predicts for recurrence and death in head-and-neck cancer. La TH, Filion EJ, Turnbull BB, Chu JN, Lee P, Nguyen K, Maxim P, Quon A, Graves EE, Loo BW, Le QT. Int J Radiat Oncol Biol Phys. 2009; 74 (5): 1335-41
• Re: "The safety and efficacy of robotic image-guided radiosurgery system treatment for intra- and extracranial lesions: a systematic review of the literature" [Radiotherapy and Oncology 89 (2009) 245-253]. Gibbs IC, Levendag PC, Fariselli L, Bondiau PY, Lartigau E, Loo BW, Gagnon GJ, Koong A. Radiother Oncol. 2009; 93 (3): 656-7
• Safety and efficacy of percutaneous fiducial marker implantation for image-guided radiation therapy. Kothary N, Heit JJ, Louie JD, Kuo WT, Loo BW, Koong A, Chang DT, Hovsepian D, Sze DY, Hofmann LV. J Vasc Interv Radiol. 2009; 20 (2): 235-9
• Stereotactic body radiotherapy for primary and oligometastatic cancers MT Spiotto, BW Loo Jr, DT Chang. Community Oncology. 2009; 6 (10): 456-462
• Complications of ablative therapies in lung cancer. Padda S, Kothary N, Donington J, Cannon W, Loo BW, Kee S, Wakelee H. Clin Lung Cancer. 2008; 9 (2): 122-6
• Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma. Hara W, Loo BW, Goffinet DR, Chang SD, Adler JR, Pinto HA, Fee WE, Kaplan MJ, Fischbein NJ, Le QT. Int J Radiat Oncol Biol Phys. 2008; 71 (2): 393-400
• Initial evaluation of 18F-fluorothymidine (FLT) PET/CT scanning for primary pancreatic cancer. Quon A, Chang ST, Chin F, Kamaya A, Dick DW, Loo BW, Gambhir SS, Koong AC. Eur J Nucl Med Mol Imaging. 2008; 35 (3): 527-31
• Post-operative radiation therapy (PORT) in completely resected non-small-cell lung cancer. Krupitskaya Y, Loo BW. Curr Treat Options Oncol. 2008; 9 (4-6): 343-56
• Retrospective analysis of artifacts in four-dimensional CT images of 50 abdominal and thoracic radiotherapy patients. Yamamoto T, Langner U, Loo BW, Shen J, Keall PJ. Int J Radiat Oncol Biol Phys. 2008; 72 (4): 1250-8
• Clinical role of 18F-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma. Quon A, Fischbein NJ, McDougall IR, Le QT, Loo BW, Pinto H, Kaplan MJ. J Nucl Med. 2007: 48 Suppl 1 58S-67S
• Impact of integrated PET/CT on variability of target volume delineation in rectal cancer. Patel DA, Chang ST, Goodman KA, Quon A, Thorndyke B, Gambhir SS, McMillan A, Loo BW, Koong AC. Technol Cancer Res Treat. 2007; 6 (1): 31-6
• Metabolic tumor burden predicts for disease progression and death in lung cancer. Lee P, Weerasuriya DK, Lavori PW, Quon A, Hara W, Maxim PG, Le QT, Wakelee HA, Donington JS, Graves EE, Loo BW. Int J Radiat Oncol Biol Phys. 2007; 69 (2): 328-33
• Quantification of motion of different thoracic locations using four-dimensional computed tomography: implications for radiotherapy planning. Maxim PG, Loo BW, Shirazi H, Thorndyke B, Luxton G, Le QT. Int J Radiat Oncol Biol Phys. 2007; 69 (5): 1395-401
• RT_Image: an open-source tool for investigating PET in radiation oncology. Graves EE, Quon A, Loo BW. Technol Cancer Res Treat. 2007; 6 (2): 111-21
• Four-dimensional cone-beam computed tomography using an on-board imager. Li T, Xing L, Munro P, McGuinness C, Chao M, Yang Y, Loo B, Koong A. Med Phys. 2006; 33 (10): 3825-33
• Indirect MR lymphangiography of the head and neck using conventional gadolinium contrast: a pilot study in humans. Loo BW, Draney MT, Sivanandan R, Ruehm SG, Pawlicki T, Xing L, Herfkens RJ, Le QT. Int J Radiat Oncol Biol Phys. 2006; 66 (2): 462-8
• Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors. Le QT, Loo BW, Ho A, Cotrutz C, Koong AC, Wakelee H, Kee ST, Constantinescu D, Whyte RI, Donington J. J Thorac Oncol. 2006; 1 (8): 802-9
• Optical detection of tumors in vivo by visible light tissue oximetry. Maxim PG, Carson JJ, Benaron DA, Loo BW, Xing L, Boyer AL, Friedland S. Technol Cancer Res Treat. 2005; 4 (3): 227-34
• Plasmablastic lymphoma presenting in a human immunodeficiency virus-negative patient: a case report. Nguyen DD, Loo BW, Tillman G, Natkunam Y, Cao TM, Vaughan W, Dorfman RF, Goffinet DR, Jacobs CD, Advani RH. Ann Hematol. 2003; 82 (8): 521-5
• A new sample preparation method for biological soft X-ray microscopy: nitrogen-based contrast and radiation tolerance properties of glycol methacrylate-embedded and sectioned tissue. Loo BW, Sauerwald IM, Hitchcock AP, Rothman SS. J Microsc. 2001; 204 (Pt 1): 69-86
• Automatic image acquisition, calibration and montage assembly for biological X-ray microscopy. Loo BW, Meyer-Ilse W, Rothman SS. J Microsc. 2000; 197 (Pt 2): 185-201
• An environmental sample chamber for x-ray microscopy Goncz KK, Batson P, Ciarlo D, Loo BW Jr, Rothman SS. J Microsc. 1992: 168 101-110
• X-ray stereomicroscopy: high resolution 3-D imaging of human spermatozoa in aqueous suspension with natural contrast. Loo BW, Williams S, Meizel S, Rothman SS. J Microsc. 1992; 166 (Pt 2): Rp5-6