Or Gozani
Publications
- A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation. Mol Cell. 2013; (3): 444-56
- Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses. Nat Struct Mol Biol. 2012; (3): 361-3
- The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome. Nature. 2012; (7392): 115-9
- Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nat Immunol. 2011; (1): 29-36
- NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Mol Cell. 2011; (4): 609-20
- ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature. 2006; (7098): 96-9
- Chd5 requires PHD-mediated histone 3 binding for tumor suppression. Cell Rep. 2013; (1): 92-102
- Correction: Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. Arthritis Res Ther. 2012; (4): 403
- Everybody's welcome: The big tent approach to epigenetic drug discovery. Drug Discov Today Ther Strateg. 2012; (2-3): e75-e81
- Methylation by Set9 modulates FoxO3 stability and transcriptional activity. Aging (Albany NY). 2012; (7): 462-79
- New marks on the block: Set5 methylates H4 lysines 5, 8 and 12. Nucleus. 2012; (4): 335-9
- On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions. Nat Med. 2012; (9): 1434-40
- Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity. Nat Struct Mol Biol. 2012; (12): 1257-65
- SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature. 2012; (7405): 114-8
- Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. Epigenetics. 2012; (4): 340-3
- Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. Arthritis Res Ther. 2012; (1): R25
- A chemical method for labeling lysine methyltransferase substrates. Chembiochem. 2011; (2): 330-4
- A proteomic approach for the identification of novel lysine methyltransferase substrates. Epigenetics Chromatin. 2011: 19
- CUL4B: trash talking at chromatin. Mol Cell. 2011; (3): 321-3
- Hypoxia-induced methylation of a pontin chromatin remodeling factor. Proc Natl Acad Sci U S A. 2011; (33): 13510-5
- Regulation of p53 function by lysine methylation. Epigenomics. 2011; (3): 361-9
- Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling. Nucleic Acids Res. 2011; (15): 6380-9
- Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates. Epigenetics. 2010 Nov-Dec; (8): 767-75
- A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation. Mol Cell. 2010; (2): 165-78
- Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription. J Mol Biol. 2010; (2): 137-44
- Decoding chromatin goes high tech. Cell. 2010; (6): 844-6
- Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature. 2010; (7304): 383-7
- Methylation of the retinoblastoma tumor suppressor by SMYD2. J Biol Chem. 2010; (48): 37733-40
- Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain. J Mol Biol. 2010; (2): 145-54
- Negative regulation of hypoxic responses via induced Reptin methylation. Mol Cell. 2010; (1): 71-85
- Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J Mol Biol. 2010; (4): 489-96
- TRIM24 links a non-canonical histone signature to breast cancer. Nature. 2010; (7326): 927-32
- The MBT repeats of L3MBTL1 link SET8-mediated p53 methylation at lysine 382 to target gene repression. J Biol Chem. 2010; (48): 37725-32
- Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6. Cell Cycle. 2009; (16): 2664-6
- Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks. PLoS One. 2009; (8): e6789
- HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail. Mol Cell. 2009; (2): 257-65
- ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation. Mol Cell. 2009; (2): 248-56
- NMR assignments and histone specificity of the ING2 PHD finger. Magn Reson Chem. 2009; (4): 352-8
- SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging (Albany NY). 2009; (1): 109-21
- The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate. J Biol Chem. 2009; (49): 34283-95
- Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity. Proc Natl Acad Sci U S A. 2008; (41): 15878-83
- Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor. J Mol Biol. 2008; (2): 303-12
- Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling. J Biol Chem. 2008; (50): 34660-6
- SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature. 2008; (7186): 492-6
- Modulation of p53 function by SET8-mediated methylation at lysine 382. Mol Cell. 2007; (4): 636-46
- Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36. J Biol Chem. 2007; (4): 2450-5
- RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature. 2007; (7172): 1106-10
- Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature. 2007; (7154): 718-22
- Stabilized phosphatidylinositol-5-phosphate analogues as ligands for the nuclear protein ING2: chemistry, biology, and molecular modeling. J Am Chem Soc. 2007; (20): 6498-506
- The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proc Natl Acad Sci U S A. 2007; (48): 18993-8
- Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2. Nature. 2006; (7098): 100-3
- PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection. EMBO J. 2006; (5): 1024-34
- The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3. Mol Cell Biol. 2006; (21): 7871-9
- A PHD finger motif in the C terminus of RAG2 modulates recombination activity. J Biol Chem. 2005; (31): 28701-10
- Modification of protein sub-nuclear localization by synthetic phosphoinositides: evidence for nuclear phosphoinositide signaling mechanisms. Adv Enzyme Regul. 2005: 171-85
- The fellowships of the INGs. J Cell Biochem. 2005; (6): 1127-36
- The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell. 2003; (1): 99-111
- Life and death in paradise. Nat Cell Biol. 2002; (6): E159-62
- The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death. Mol Cell. 2001; (6): 1307-19
- Characterization of a protein complex containing spliceosomal proteins SAPs 49, 130, 145, and 155. Mol Cell Biol. 1999; (10): 6796-802
- A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site. Mol Cell Biol. 1998; (8): 4752-60
- Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells. Mol Cell Biol. 1998; (8): 4526-36
- Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis. Genes Dev. 1998; (10): 1409-14
- Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A. Genes Dev. 1996; (2): 233-43
- Identification of proteins that interact with exon sequences, splice sites, and the branchpoint sequence during each stage of spliceosome assembly. Mol Cell Biol. 1996; (7): 3317-26
- Accumulation of a novel spliceosomal complex on pre-mRNAs containing branch site mutations. Mol Cell Biol. 1995; (10): 5750-6
- A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction. EMBO J. 1994; (14): 3356-67
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