Guowei Fang
Publications
- Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry. Science. 2008; (5883): 1655-8
- DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement. J Cell Biol. 2008; (2): 255-67
- Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression. J Cell Biol. 2008; (1): 65-78
- RCS1, a substrate of APC/C, controls the metaphase to anaphase transition. Proc Natl Acad Sci U S A. 2008; (36): 13415-20
- Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitope. J Cell Biol. 2007; (4): 611-7
- HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture. J Cell Biol. 2006; (6): 879-91
- Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain. Mol Biol Cell. 2008; (5): 2083-91
- CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit. J Biol Chem. 2007; (20): 15103-13
- Centromere cohesion: regulating the guardian. Cell Res. 2007; (8): 664-5
- Cep55, a microtubule-bundling protein, associates with centralspindlin to control the midbody integrity and cell abscission during cytokinesis. Mol Biol Cell. 2006; (9): 3881-96
- Loading of the 3F3/2 antigen onto kinetochores is dependent on the ordered assembly of the spindle checkpoint proteins. Mol Biol Cell. 2006; (10): 4390-9
- Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit. Mol Cell Biol. 2005; (23): 10516-27
- Anillin is a substrate of anaphase-promoting complex/cyclosome (APC/C) that controls spatial contractility of myosin during late cytokinesis. J Biol Chem. 2005; (39): 33516-24
- Chfr is required for tumor suppression and Aurora A regulation. Nat Genet. 2005; (4): 401-6
- Destruction box-dependent degradation of aurora B is mediated by the anaphase-promoting complex/cyclosome and Cdh1. Cancer Res. 2005; (19): 8730-5
- MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis. Proc Natl Acad Sci U S A. 2005; (37): 13158-63
- Plx1 is the 3F3/2 kinase responsible for targeting spindle checkpoint proteins to kinetochores. J Cell Biol. 2005; (5): 709-19
- A Xenopus cell-free system for analysis of the Chfr ubiquitin ligase involved in control of mitotic entry. Methods Mol Biol. 2004: 229-43
- Spindle checkpoint protein dynamics at kinetochores in living cells. Curr Biol. 2004; (11): 953-64
- Breast cancer-specific gene 1 interacts with the mitotic checkpoint kinase BubR1. Oncogene. 2003; (48): 7593-9
- Determining the position of the cell division plane. Nature. 2003; (6952): 1074-8
- Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores. Curr Biol. 2003; (23): 2103-9
- Anaphase onset does not require the microtubule-dependent depletion of kinetochore and centromere-binding proteins. J Cell Sci. 2002; (Pt 19): 3787-95
- Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex. Mol Biol Cell. 2002; (3): 755-66
- Cyclin B and E2F-1 expression in prostate carcinoma cells treated with the novel retinoid CD437 are regulated by the ubiquitin-mediated pathway. Cancer Res. 2002; (13): 3842-9
- Inducing precocious anaphase in cultured mammalian cells. Cell Motil Cytoskeleton. 2002; (2): 61-5
- The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition. J Cell Biol. 2002; (2): 249-59
- MAD2B is an inhibitor of the anaphase-promoting complex. Genes Dev. 2001; (14): 1765-70
- Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat Struct Biol. 2000; (3): 224-9
- Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells. J Cell Biol. 2000; (6): 1233-50
- Control of mitotic transitions by the anaphase-promoting complex. Philos Trans R Soc Lond B Biol Sci. 1999; (1389): 1583-90
- Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. Mol Cell. 1998; (2): 163-71
- The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev. 1998; (12): 1871-83
- Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates. J Cell Biol. 1995; (2): 243-53
- Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein. Biochemistry. 1993; (43): 11646-57
- Oxytricha telomere-binding protein: DNA-dependent dimerization of the alpha and beta subunits. Proc Natl Acad Sci U S A. 1993; (13): 6056-60
- Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the alpha-subunit. Genes Dev. 1993; (5): 870-82
- The beta subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA. Cell. 1993; (5): 875-85
- Molecular cloning of telomere-binding protein genes from Stylonychia mytilis. Nucleic Acids Res. 1991; (20): 5515-8
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