Jonathan Pollack
Publications
- Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types. PLoS Genet. 2013; (4): e1003464
- EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms. Oncogene. 2013; (21): 2670-2681
- The spectrum of SWI/SNF mutations, ubiquitous in human cancers. PLoS One. 2013; (1): e55119
- CDX2 is an amplified lineage-survival oncogene in colorectal cancer. Proc Natl Acad Sci U S A. 2012; (46): E3196-205
- Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer. Proc Natl Acad Sci U S A. 2012; (5): E252-9
- Recurrent deletion of CHD1 in prostate cancer with relevance to cell invasiveness. Oncogene. 2012; (37): 4164-70
- A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancer. PLoS One. 2011; (5): e20293
- SMURF1 amplification promotes invasiveness in pancreatic cancer. PLoS One. 2011; (8): e23924
- DR-Integrator: a new analytic tool for integrating DNA copy number and gene expression data. Bioinformatics. 2010; (3): 414-6
- Development of an orthotopic model of invasive pancreatic cancer in an immunocompetent murine host. Clin Cancer Res. 2010; (14): 3684-95
- Focal amplification and oncogene dependency of GAB2 in breast cancer. Oncogene. 2010; (5): 774-9
- Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer. Oncogene. 2010; (10): 1421-30
- Genomic instability in breast cancer: pathogenesis and clinical implications. Mol Oncol. 2010; (3): 255-66
- KIT mutations confer a distinct gene expression signature in core binding factor leukaemia. Br J Haematol. 2010; (6): 925-37
- LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer. Cancer Res. 2010; (6): 2296-306
- Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. Cancer Res. 2010; (16): 6477-85
- Comparative genomic hybridization on spotted oligonucleotide microarrays. Methods Mol Biol. 2009: 21-32
- DNA microarray technology. Introduction. Methods Mol Biol. 2009: 1-6
- Integration of diverse microarray data types. Methods Mol Biol. 2009: 205-16
- Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery. PLoS One. 2009; (7): e6146
- An FLT3 gene-expression signature predicts clinical outcome in normal karyotype AML. Blood. 2008; (9): 4490-5
- CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer. Mol Oncol. 2008; (4): 327-39
- ESR1 gene amplification in breast cancer: a common phenomenon? Nat Genet. 2008; (7): 807-8; author reply 810-2
- Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer. PLoS Genet. 2008; (5): e1000081
- Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer. Oncogene. 2008; (25): 3635-40
- Identification of candidate prostate cancer genes through comparative expression-profiling of seminal vesicle. Prostate. 2008; (11): 1248-56
- Interlaboratory performance of a microarray-based gene expression test to determine tissue of origin in poorly differentiated and undifferentiated cancers. J Mol Diagn. 2008; (1): 67-77
- MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood. 2008; (10): 4202-12
- hCAP-D3 expression marks a prostate cancer subtype with favorable clinical behavior and androgen signaling signature. Am J Surg Pathol. 2008; (2): 205-9
- A perspective on DNA microarrays in pathology research and practice. Am J Pathol. 2007; (2): 375-85
- A variant TMPRSS2 isoform and ERG fusion product in prostate cancer with implications for molecular diagnosis. Mod Pathol. 2007; (4): 467-73
- Evolutionary and biomedical insights from the rhesus macaque genome. Science. 2007; (5822): 222-34
- Gene copy number variation spanning 60 million years of human and primate evolution. Genome Res. 2007; (9): 1266-77
- Gene-expression profiling identifies distinct subclasses of core binding factor acute myeloid leukemia. Blood. 2007; (4): 1291-300
- Genomic profiling reveals alternative genetic pathways of prostate tumorigenesis. Cancer Res. 2007; (18): 8504-10
- Target discovery and validation in pancreatic cancer. Methods Mol Biol. 2007: 57-89
- c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells. Oncogene. 2007; (18): 2658-66
- A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. PLoS Med. 2006; (12): e486
- Amplification of EMSY, a novel oncogene on 11q13, in high grade ovarian surface epithelial carcinomas. Gynecol Oncol. 2006; (2): 264-70
- Application of genomic technologies to human prostate cancer. OMICS. 2006; (3): 261-75
- Chromosome instability leaves its mark. Nat Genet. 2006; (9): 973-4
- Combined microarray analysis of small cell lung cancer reveals altered apoptotic balance and distinct expression signatures of MYC family gene amplification. Oncogene. 2006; (1): 130-8
- DNA microarray and proteomic strategies for understanding alcohol action. Alcohol Clin Exp Res. 2006; (4): 700-8
- Disclosure of candidate genes in acute myeloid leukemia with complex karyotypes using microarray-based molecular characterization. J Clin Oncol. 2006; (24): 3887-94
- Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer. Genes Chromosomes Cancer. 2006; (11): 1033-40
- Expression of tumor-associated antigens in acute myeloid leukemia: Implications for specific immunotherapeutic approaches. Blood. 2006; (13): 4109-17
- Molecular profiling reveals myeloid leukemia cell lines to be faithful model systems characterized by distinct genomic aberrations. Leukemia. 2006; (6): 994-1001
- RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes. Genes Chromosomes Cancer. 2006; (8): 761-9
- A DNA microarray survey of gene expression in normal human tissues. Genome Biol. 2005; (3): R22
- A gene expression signature of genetic instability in colon cancer. Cancer Res. 2005; (20): 9200-5
- A method for calling gains and losses in array CGH data. Biostatistics. 2005; (1): 45-58
- Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer. Cancer Res. 2005; (1): 226-35
- Amplification of whole tumor genomes and gene-by-gene mapping of genomic aberrations from limited sources of fresh-frozen and paraffin-embedded DNA. J Mol Diagn. 2005; (2): 171-82
- An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin. Cancer Res. 2005; (10): 4031-40
- Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer. Neoplasia. 2005; (6): 556-62
- Comparative genomic hybridization on mouse cDNA microarrays and its application to a murine lymphoma model. Oncogene. 2005; (40): 6101-7
- Genome-wide characterization of gene expression variations and DNA copy number changes in prostate cancer cell lines. Prostate. 2005; (2): 187-97
- Genomics in myeloid leukemias: an array of possibilities. Rev Clin Exp Hematol. 2005; (1): E2
- The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer. Cancer Res. 2005; (18): 8118-24
- Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc Natl Acad Sci U S A. 2004; (3): 811-6
- High-resolution array-based comparative genomic hybridization for distinguishing paraffin-embedded Spitz nevi and melanomas. Diagn Mol Pathol. 2004; (1): 22-5
- Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res. 2004; (24): 9027-34
- Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol. 2004; (7): E207
- Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N Engl J Med. 2004; (16): 1605-16
- Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans. Am J Pathol. 2003; (6): 2383-95
- Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray. Am J Pathol. 2003; (3): 925-32
- Gene expression profiling in prostate cancer cells with Akt activation reveals Fra-1 as an Akt-inducible gene. Mol Cancer Res. 2003; (6): 475-84
- Parallel analysis of gene copy number and expression using cDNA microarrays. Methods Mol Biol. 2003: 89-97
- The diagnosis and management of pre-invasive breast disease: promise of new technologies in understanding pre-invasive breast lesions. Breast Cancer Res. 2003; (6): 320-8
- A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol. 2002: 8
- Challenges in developing a molecular characterization of cancer. Semin Oncol. 2002; (3): 280-5
- Characterizing the physical genome. Nat Genet. 2002: 515-21
- Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors. Proc Natl Acad Sci U S A. 2002; (20): 12963-8
- Molecular characterisation of soft tissue tumours: a gene expression study. Lancet. 2002; (9314): 1301-7
- Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays. Genome Biol. 2002; (6): RESEARCH0026
- Molecular portraits of human breast tumours. Nature. 2000; (6797): 747-52
- Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nat Genet. 1999; (1): 41-6
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