Anne Brunet
Publications
- Bridging the transgenerational gap with epigenetic memory. Trends Genet. 2013; (3): 176-86
- Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nat Cell Biol. 2013
- FOXO flips the longevity SWItch. Nat Cell Biol. 2013; (5): 444-6
- Aging and reprogramming: a two-way street. Curr Opin Cell Biol. 2012; (6): 744-56
- Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis. Mol Cell. 2011; (6): 878-92
- Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature. 2011; (7373): 365-71
- Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate. J Cell Sci. 2012; (Pt 23): 5597-608
- Histone methylation makes its mark on longevity. Trends Cell Biol. 2012; (1): 42-9
- Methylation by Set9 modulates FoxO3 stability and transcriptional activity. Aging (Albany NY). 2012; (7): 462-79
- [Aging and the control of the insulin-FOXO signaling pathway]. Med Sci (Paris). 2012; (3): 316-20
- A CRTCal link between energy and life span. Cell Metab. 2011; (4): 358-60
- Energy metabolism in adult neural stem cell fate. Prog Neurobiol. 2011; (2): 182-203
- Epigenetic regulation of aging stem cells. Oncogene. 2011; (28): 3105-26
- MicroRNA programs in normal and aberrant stem and progenitor cells. Genome Res. 2011; (5): 798-810
- The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner. Aging Cell. 2011; (6): 980-90
- The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. Aging (Albany NY). 2011; (2): 108-24
- The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. Oncogene. 2011; (29): 3207-21
- Transposon-Mediated Transgenesis in the Short-Lived African Killifish Nothobranchius furzeri, a Vertebrate Model for Aging. G3 (Bethesda). 2011; (7): 531-8
- Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature. 2010; (7304): 383-7
- AMP-activated protein kinase and FoxO transcription factors in dietary restriction-induced longevity. Ann N Y Acad Sci. 2009: 688-92
- Cancer: When restriction is good. Nature. 2009; (7239): 713-4
- Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell. 2009; (2): 113-27
- FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell. 2009; (5): 527-39
- Mapping loci associated with tail color and sex determination in the short-lived fish Nothobranchius furzeri. Genetics. 2009; (4): 1385-95
- FOXO transcription factors in ageing and cancer. Acta Physiol (Oxf). 2008; (1): 19-28
- FoxO transcription factors in the maintenance of cellular homeostasis during aging. Curr Opin Cell Biol. 2008; (2): 126-36
- Signaling networks in aging. J Cell Sci. 2008; (Pt 4): 407-12
- The FoxO code. Oncogene. 2008; (16): 2276-88
- Ageing: from stem to stern. Nature. 2007; (7160): 288-91
- Aging and cancer: killing two birds with one worm. Nat Genet. 2007; (11): 1306-7
- An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr Biol. 2007; (19): 1646-56
- FOXO transcription factors. Curr Biol. 2007; (4): R113-4
- The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem. 2007; (41): 30107-19
- FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene. 2005; (50): 7410-25
- Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science. 2004; (5666): 2011-5
- PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation. J Biol Chem. 2003; (52): 52587-97
- The many forks in FOXO's road. Sci STKE. 2003; (172): RE5
- 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport. J Cell Biol. 2002; (5): 817-28
- DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science. 2002; (5567): 530-4
- Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol. 2001; (3): 952-65
- Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr Opin Neurobiol. 2001; (3): 297-305
- Transforming growth factor beta enhances epithelial cell survival via Akt-dependent regulation of FKHRL1. Mol Biol Cell. 2001; (11): 3328-39
- Substrate recognition domains within extracellular signal-regulated kinase mediate binding and catalytic activation of mitogen-activated protein kinase phosphatase-3. J Biol Chem. 2000; (32): 24613-21
- Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell. 1999; (6): 857-68
- Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science. 1999; (5443): 1358-62
- Cellular survival: a play in three Akts. Genes Dev. 1999; (22): 2905-27
- Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. EMBO J. 1999; (3): 664-74
- Growth factor-induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteins. J Cell Biol. 1998; (3): 625-33
- Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation. J Biol Chem. 1998; (16): 9966-70
- Involvement of extracellular signal-regulated kinase module in HIV-mediated CD4 signals controlling activation of nuclear factor-kappa B and AP-1 transcription factors. J Immunol. 1998; (4): 1875-85
- [Signal transduction from the membrane to the nucleus: variations on common themes]. Bull Cancer. 1998; (6): 527-37
- Mammalian MAP kinase modules: how to transduce specific signals. Essays Biochem. 1997: 1-16
- The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44MAPK cascade. J Biol Chem. 1997; (2): 1368-76
- Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J Biol Chem. 1996; (34): 20608-16
- Identification of MAP kinase domains by redirecting stress signals into growth factor responses. Science. 1996; (5268): 1652-5
- B-Raf protein isoforms interact with and phosphorylate Mek-1 on serine residues 218 and 222. Oncogene. 1995; (8): 1647-51
- The mouse p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1) gene. Genomic organization and structure of the 5'-flanking regulatory region. J Biol Chem. 1995; (45): 26986-92
- [MAP kinase module: role in the control of cell proliferation]. C R Seances Soc Biol Fil. 1995; (1): 43-57
- Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1). EMBO J. 1994; (13): 3003-10
- Constitutively active mutants of MAP kinase kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts. Oncogene. 1994; (11): 3379-87
- Growth factor-stimulated MAP kinase induces rapid retrophosphorylation and inhibition of MAP kinase kinase (MEK1). FEBS Lett. 1994; (2-3): 299-303
- Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts. J Cell Biol. 1993; (5): 1079-88
Help
Trial Administration